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So, Where Are The Best Drug Blogs?

It’s about time we dug out some of the best drug blogs on t’internet. I ori­gin­ally started this blog because there wasn’t any­thing else decent to read, or what was avail­able was too obscure to be found easily, but there’s much more out there now.

I thought we could collect up a nice list of sug­ges­tions from you lot, maybe have a vote, then produce a list of the top drug blogs that every­one should be reading.

Let’s have some sug­ges­tions in the com­ments then!

(Oh, and the new misses is sup­posed to be writing summary of our hon­ey­moon in t’Dominican Repub­lic, but it seems that she’s been spend­ing all her time in the kitchen since we’ve been back. I’ll have a word…).

Posted in Drugs | Tagged bloggers, drug blogs, websites |

lolwut?

Yep, that’s right. It’s a dolphin on a jetski smoking a doob.

Doob Smokin' Dolphin

Although many Botham spies didn’t die to bring you this picture, Jo had to take the pic with her phone, text it to my phone which doesn’t have picture mes­saging set up (I know, I know), so I could then access it through my network’s website, down­load it and upload it here. Worth it? We think so.

We’re still on hon­ey­moon for a few more days, so look out for a proper update towards the end of next week.

See all y’all soon..

Posted in Personal | Tagged dolphin, doob, honeymoon, wedding |

The Effects of a Novel, Putative 5-HT2a Receptor Agonist on the Creative Process

For my stag night me and a few mates sat in a dark smoke-filled room, having inges­ted a safe amount of legal and uniden­ti­fi­able chem­ical, in pos­ses­sion of a shitty key­board, an awesome syn­thes­izer, an ancient drum machine and some kind of stly­ophone, all fed through a very expens­ive bass amp. There was also an acous­tic guitar lying around.

None of us are very good at music, but this is what we somehow came up with. It was recor­ded with a phone in the middle of the room.

The Track

It’s not exactly awesome, but I thought I’d stick it up here anyway for you to laugh at, more than any­thing.

Right, I’m off on hon­ey­moon in 9 hours. I’ll write some­thing else when I get back! Off in half an hour — see you all in two weeks!.

Posted in Personal | Tagged 5-ht2a, hallucinogens, Music On Drugs |

We're Married!

In case you were won­der­ing why I’ve not written any­thing decent for ages, it’s because we’ve been plan­ning our wedding, which finally happened on Sat­urday (May 29th, 2010). I thought I’d put a couple of photos on here today because a few of you seem to actu­ally give a shit, and also then there’s less chance of me for­get­ting any future anniversar­ies.

If you’ve ever had a decent night out in Birm­ing­ham, you may recog­nise that as The Custard Factory

During the cere­mony

Us in some “arty” doorway

Also, since I’ve still not written a Music On Drugs post, you might like to give some of the music we used in the cere­mony a listen. Links to YouTube open in a new tab/​window.

Before The Cere­mony:

Jo Walking Up The Aisle:

Zero 7 — Pop Art Blue

Signing The Register:

Us Walking Out:

Lamb — Gorecki (started at 2:27)

Secular wed­dings are awesome!

(Image credit: Photos of my Wedding).

Posted in Personal | Tagged music, photos, wedding |

Science Joke Winners

Everyone’s a winner who entered last weeks Science Joke Com­pet­i­tion! Not in the sense that every­one wins a prize, but in the sense that maybe, just maybe, we’ve inspired someone, some­where to do some­thing vaguely sci­entific. So who did win a prize? …

The Winner

Potter

There is this farmer who is having prob­lems with his chick­ens. All of the sudden, they are all getting very sick and he doesn’t know what is wrong with them. After trying all con­ven­tional means, he calls a bio­lo­gist, a chemist, and a phys­i­cist to see if they can figure out what is wrong. So the bio­lo­gist looks at the chick­ens, exam­ines them a bit, and says he has no clue what could be wrong with them. Then the chemist takes some tests and makes some meas­ure­ments, but he can’t come to any con­clu­sions either. So the phys­i­cist tries. He stands there and looks at the chick­ens for a long time without touch­ing them or any­thing. Then all of the sudden he starts scrib­bling away in a note­book. Finally, after several grue­some cal­cu­la­tions, he exclaims, ‘I’ve got it! But it only works for spher­ical chick­ens in a vacuum.

The Runners Up

James

Wanted, dead AND alive: Schrödinger’s Cat

psiphi

Some helium floats into a bar, the bar­tender says “We don’t serve helium in here.”

The helium doesn’t react.

Fant­astic! Remem­ber though, if you’re not from the UK and you want to claim your prize, you’ll have to send us a couple of quid to cover the postage. We’ll sort all that out later. I’ll be in touch soon, prob­ably, although we are getting married in 6 days, so there might be a bit of a delay… :^|

I’ve got to go and write my speech now, so I’ll leave you with this bril­liant sketch from That Mitchell & Webb Look:

.

Posted in Competitions | Tagged blue lagoon, competition, entheogens, legal highs, mexican dream herb |

Science-Based Quick Competition

Fol­low­ing some rather depress­ing blog com­ments, I reckon it’s about time we had another com­pet­i­tion in the name of science!

What Can You Win?

Blue LagoonBlue Lagoon

The winner will get a super awesome double size bottle of Blue Lagoon, a new liquid herbal high, and a 10g bag of Mexican Dream Herb. The two runners up will just get the Dream Herb.

What Do You Have To Do?

I want to hear the best science joke you’ve got. There’s a few to get you started at the end of this post. Obvi­ously, I don’t expect you to write some new comedy gold, but at least have the decency to tell a joke in your own words and not just lift it from the first google result for “science joeks lol”. Post your entries in the com­ments below this post!

Who Can Enter?

If you’re in the UK, this com­pet­i­tion is for you. If you live any­where else, you can still win the stuff, just as long as you’re willing to PayPal me the postage costs. Usual rules apply, like being over 18, not men­tally unstable or preg­nant.

When Will The Winners Be Picked?

Over the next weekend prob­ably. Who knows when exactly… depends when I’ve got 5 minutes. Get off my case already! Jeez..

Posted in Drugs | Tagged blue lagoon, competition, entheogens, legal highs, mexican dream herb |

Synthetic Cannabinoid Discussion

Drugs Discussion


UPDATE: This thread is now closed. Please con­tinue the dis­cus­sion here: Syn­thetic Can­nabin­oid Dis­cus­sion II

This post is now the place to comment on the JWH-018 Tox­ic­o­logy article.

Not that there are any points, but bonus points for backing up what you say with peer reviewed research. Please keep the dis­cus­sion sci­entific. You can talk about dodgy vendors if you must, espe­cially if there’s a bad batch going round, but please don’t link to them or turn this into a cus­tomer support thread. If you want to talk about indi­vidual smoking mix­tures, please do so Here.

Ok, go:.

Posted in Pharmacology | Tagged binding affinities, cannabinoid receptors, JWH-018, jwh-073, synthetic cannabinoids, toxicology |

Smoking Mix Discussion

Drugs Discussion

I’m cre­at­ing this post so you lot can discuss smoking mix­tures. Feel free to talk about the pros and cons of dif­fer­ent indi­vidual products, but don’t talk about the vendors them­selves. Com­ments like ‘This shiz I got from buy​drugslmao​.com is suh­weeet” will be deleted.

Ok, go:.

Posted in Drugs | Tagged discussion, smoking mixtures |

How To Make A Bomb

No, this post won’t be a detailed guide to clandes­tine hexa­methyl­ene triper­ox­ide diamine man­u­fac­ture, sorry! Instead of ter­ror­ism, today’s post will focus on a great harm reduc­tion tech­nique called bombing (or para­chut­ing for us in the far-less-extreme UK).

The Problem:

You have a bag of a drugs. That bag of drugs can be snorted, or it can be eaten.  Unfor­tu­nately, your nose wasn’t meant for hoover­ing up monster lines of chem­ical. Apart from the phys­ical irrit­a­tion to your del­ic­ate mucous mem­branes, vaso­con­strict­ive drugs like cocaine or mephed­rone will restrict blood­flow in the vessels lining your nose, which could lead to ischaemia, or the damage of tissue as a result of poor blood per­fu­sion. If that wasn’t bad enough, pretty soon, your nose might start pouring with snot or just feel bunged up when the drug wears off, as the blood vessels open back up to com­pensate — your nose isn’t blocked with snot or drugs neces­sar­ily, but by these vessels filling up with blood, which closes off your nos­trils, making it harder to breath.

Suppose at this point, you still have most of your massive bag of drugs left — what do you do? Perhaps the most instinct­ive thing to do is reach for some­thing to unblock your nose, such as a decon­gest­ant spray or some “Vaporub” type stuff, so you can con­tinue your hedon­istic nasally-ori­ent­ated pleas­ure-binge. It might sur­prise you to learn that this won’t help out your sting­ing nos­trils as much as you think. These kind of products work by con­strict­ing those same blood vessels that were con­stric­ted earlier, adding to the ischaemia. If that wasn’t enough, con­tin­ued use of these kinds of products could give you rebound con­ges­tion — as soon as you stop using them, your vessels open back up to com­pensate and before you know it, you’re adding an extra “b” to every word you say ended with a bil­a­bial phone.

That’s just the phys­ical side of things. Snort­ing drugs does get them into your blood faster, sure, but this also makes whatever you’re snort­ing more addict­ive. With our old friend mephed­rone, snort­ing cer­tainly can be fun, but it’s much easier to have “just one more line” another ten times in the same session than if you ate it.

The Solution:

If your bag of drugs also works well when eaten, eat that shit! Obvi­ously no one wants to be chuck­ing fist­fulls of dis­gust­ing powder into their mouths, which is where our friend the bomb comes into play.

Step 1: Get Your Shit Together


You will need:

  • Rizlas (or whatever brand of rolling paper is most pre­val­ent where you’re from)
  • A bag of drugs
  • Some­thing to trans­fer the drugs from the bag to the papers

Step 2: Take A Single Paper

Step 3: Tear Off The Excess


You don’t need much, prob­ably about an inch or so.

Step 4: Transfer Your Drugs To The Paper


Safety first! If your drug of choice requires only a few mili­grams, or you’re gen­er­ally unsure how to eyeball a dose, weigh it out first, then trans­fer it to the paper.

Step 5: Pick Up The Paper


Get the paper to fold nat­ur­ally, as though you’re about to roll the world’s tiniest joint packed with chem­ic­als.

Step 6: Pinch The Paper


Pinch one end of the paper, so you can hold it at an angle and tap the powder into the pinched end.

Step 7: Pinch T'Other Side


Repeat step 6 with the other side, so the powder takes up as little room as pos­sible.

Step 8: Pinch Both Sides


This step should get your little pile of drugs in the centre of your paper. Don’t be afraid to com­press it a little so it stays in place. The last thing you want is stray drugs working them­selves free and onto your taste buds.

Step 9: Begin To Form A Tail


No, don’t actu­ally grow a tail. Just pull together the pinched ends of the paper, so the drugs are at one end and the free bits are together at the other.

Step 10: Form A Tail


Pinch all the excess paper into one clump between your thumb and finger.

Step 11: Complete The Tail


Now roll the tail betwixt your thumb and finger to tighten it. Feel free to lick your fingers first to help it seal, but not too much, or you’ll be left with a wet powdery mess.

Step 12: Marvel At Your Creation


Now it’s time to stick it to the infidel! Erm, I mean, take your drugs safely.

Nice work!

(Pic­tures provided by methuselah969).

Posted in Teks | Tagged bombing, harm reduction, parachuting |

Mephedrone Banned On Friday 16th April

Fol­low­ing the ACMD’s report on the cath­inone deriv­at­ives (Part I & Part II), here is the latest amend­ment to the Misuse of Drugs Act to control them:

Dan­ger­ous Drugs, England And Wales
Dan­ger­ous Drugs, Scot­land
The Misuse of Drugs (Amend­ment) (England, Wales and Scot­land) Reg­u­la­tions 2010

Made
31st March 2010

Laid before Par­lia­ment
1st April 2010

Coming into force
16th April 2010

The Sec­ret­ary of State makes the fol­low­ing Reg­u­la­tions in exer­cise of the powers con­ferred by sec­tions 7, 10, 22 and 31 of the Misuse of Drugs Act 1971(1).

In accord­ance with section 31(3) of that Act the Sec­ret­ary of State has con­sul­ted with the Advis­ory Council on the Misuse of Drugs.
Cita­tion, com­mence­ment, inter­pret­a­tion and extent

1. — (1) These Reg­u­la­tions may be cited as the Misuse of Drugs (Amend­ment) (England, Wales and Scot­land) Reg­u­la­tions 2010 and shall come into force on 16th April 2010.

(2) In these Reg­u­la­tions “the 2001 Reg­u­la­tions” means the Misuse of Drugs Reg­u­la­tions 2001(2).

(3) These Reg­u­la­tions extend to England, Wales and Scot­land.
Amend­ment to the 2001 Reg­u­la­tions

2. The 2001 Reg­u­la­tions shall be amended as follows.

3. In Sched­ule 1 (which spe­cifies con­trolled drugs subject to the require­ments of reg­u­la­tions 14, 15, 16, 18, 19, 20, 23, 26 and 27)—

(a) in para­graph 1(a), after “meth­cath­inone”, insert—

“4 – methyl­meth­cath­inone”;

(b) after para­graph 1(l), insert—

“(m) Any com­pound (not being bupro­pion, diethyl­pro­pion, pyro­va­ler­one or a com­pound for the time being spe­cified in sub – para­graph (a) above) struc­tur­ally derived from 2 – amino – 1 – phenyl – 1 – pro­pan­one by modi­fic­a­tion in any of the fol­low­ing ways, that is to say—

(i) by sub­sti­tu­tion in the phenyl ring to any extent with alkyl, alkoxy, alkyle­ne­di­oxy, haloal­kyl or halide sub­stitu­ents, whether or not further sub­sti­tuted in the phenyl ring by one or more other uni­valent sub­stitu­ents;

(ii) by sub­sti­tu­tion at the 3 – pos­i­tion with an alkyl sub­stitu­ent;

(iii) by sub­sti­tu­tion at the nitro­gen atom with alkyl or dialkyl groups, or by inclu­sion of the nitro­gen atom in a cyclic struc­ture.”.

David Hanson
Min­is­ter of State
Home Office
31st March 2010

Let’s take a look at this and try and make some sense of it shall we?

(a) in para­graph 1(a), after “meth­cath­inone”, insert—

“4 – methyl­meth­cath­inone”;

First off, mephed­rone (4-methyl­meth­cath­inone) is expli­citly men­tioned to appear after meth­cath­inone, which is already class B. I suppose we knew that much was going to happen already, so onto the more com­plic­ated stuff…

(b) after para­graph 1(l), insert—

“(m) Any com­pound (not being bupro­pion, diethyl­pro­pion, pyro­va­ler­one or a com­pound for the time being spe­cified in sub – para­graph (a) above) struc­tur­ally derived from 2 – amino – 1 – phenyl – 1 – pro­pan­one by modi­fic­a­tion in any of the fol­low­ing ways, that is to say—

This means that any cath­inone deriv­at­ive described by any of the fol­low­ing para­graphs will also become class B. Like the can­nabin­oids banned last Decem­ber, this ban doesn’t list a tonne of indi­vidual sub­stances, but instead covers a wide range of actual and the­or­et­ical sub­stances by detail­ing pos­sible alter­a­tions to the ori­ginal cath­inone struc­ture. Here they are:

(i) by sub­sti­tu­tion in the phenyl ring to any extent with alkyl, alkoxy, alkyle­ne­di­oxy, haloal­kyl or halide sub­stitu­ents, whether or not further sub­sti­tuted in the phenyl ring by one or more other uni­valent sub­stitu­ents;

This first part covers modi­fic­a­tions of the phenyl ring, or “round bit” of the cath­inone struc­ture (R4). Unfor­tu­nately, this covers a massive range of com­pounds, includ­ing Mephed­rone (alkyl), Methed­rone (alkoxy), Methyl­one, Ethyl­one, Butylone & MDPV (all alkyle­ne­di­oxy) and flephed­rone (halide; also includes the 3-F isomer) .

(ii) by sub­sti­tu­tion at the 3 – pos­i­tion with an alkyl sub­stitu­ent;

This covers the addi­tion of a carbon side chain of any length on the carbon atom just before the nitro­gen atom (usually referred to as the alpha carbon).  All the com­pounds listed in Annex A,  Appendix 1 of the ACMD’s report include a chain of at least one carbon long (alpha methyl­a­tion), but by not spe­cify­ing the length of this “alkyl sub­sti­tute”, this also covers  exist­ing com­pounds with longer alpha side chains such as pentylone and MDPV as well as any poten­tially inter­est­ing the­or­et­ical com­pounds.

(iii) by sub­sti­tu­tion at the nitro­gen atom with alkyl or dialkyl groups, or by inclu­sion of the nitro­gen atom in a cyclic struc­ture.”

The final nitro­gen atom present in cath­inone has two avail­able places to add stuff. One or both of these could be a carbon chain (alkyl or dialkyl), or a single carbon chain could form a ring by start­ing and ending at this nitro­gen atom (the “cyclic struc­ture”), which is what this part covers. Examples include eth­cath­inone (alkyl — a single carbon chain), n,n-dimethylcathinone (dialkyl — two carbon chains) and MDPV (includes the cyclic pyrrolid­inyl struc­ture).

I know that’s still quite tech­nical, but hope­fully what I’ve written is a little clearer than the ori­ginal text. Feel free to ask ques­tions in the com­ments though!

The gist is, all the popular cath­inone deriv­at­ives men­tioned by name above will become class B on Friday 16th, as well as a great deal of the more eso­teric ones. One com­pound not included in this ban is naphyrone, cur­rently mar­keted as Energy-1 or NRG-1. Unfor­tu­nately, I hear it’s rather shit and also not par­tic­u­larly safe, but the ACMD are already looking into banning that for next time. That’s pretty much it for cath­inones in the UK then. I feel like we should all go out and get com­mem­or­ative T-shirts or some­thing… 🙁

On a more serious note, for those pre­vi­ously law abiding cit­izens who have developed a psy­cho­lo­gical addic­tion to mephed­rone, you have two choices: con­tinue buying lower quality stuff at an inflated price from a regular drug dealer or find some help. Luckily, Drug​-Forum​.com has a great Recov­ery and Addic­tion section that you should def­in­itely check out.  You’re also welcome to post your stories and pro­gress in the com­ments under this post..

Posted in Legislation | Tagged ACMD, addiction, butylone, cathinone, classification, dimethylcathinone, energy-1, ephedrone, mdpv, mephedrone, methylone, naphyrone, nrg-1, pentylone |