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So, Where Are The Best Drug Blogs?

It’s about time we dug out some of the best drug blogs on t’internet. I originally started this blog because there wasn’t anything else decent to read, or what was available was too obscure to be found easily, but there’s much more out there now.

I thought we could collect up a nice list of suggestions from you lot, maybe have a vote, then produce a list of the top drug blogs that everyone should be reading.

Let’s have some suggestions in the comments then!

(Oh, and the new misses is supposed to be writing summary of our honeymoon in t’Dominican Republic, but it seems that she’s been spending all her time in the kitchen since we’ve been back. I’ll have a word…).

Posted in Drugs | Tagged bloggers, drug blogs, websites |

lolwut?

Yep, that’s right. It’s a dolphin on a jetski smoking a doob.

Doob Smokin' Dolphin

Although many Botham spies didn’t die to bring you this picture, Jo had to take the pic with her phone, text it to my phone which doesn’t have picture messaging set up (I know, I know), so I could then access it through my network’s website, download it and upload it here. Worth it? We think so.

We’re still on honeymoon for a few more days, so look out for a proper update towards the end of next week.

See all y’all soon..

Posted in Personal | Tagged dolphin, doob, honeymoon, wedding |

The Effects of a Novel, Putative 5-HT2a Receptor Agonist on the Creative Process

For my stag night me and a few mates sat in a dark smoke-filled room, having ingested a safe amount of legal and unidentifiable chemical, in possession of a shitty keyboard, an awesome synthesizer, an ancient drum machine and some kind of stlyophone, all fed through a very expensive bass amp. There was also an acoustic guitar lying around.

None of us are very good at music, but this is what we somehow came up with. It was recorded with a phone in the middle of the room.

The Track

It’s not exactly awesome, but I thought I’d stick it up here anyway for you to laugh at, more than anything.

Right, I’m off on honeymoon in 9 hours. I’ll write something else when I get back! Off in half an hour – see you all in two weeks!.

Posted in Personal | Tagged 5-ht2a, hallucinogens, Music On Drugs |

We’re Married!

In case you were wondering why I’ve not written anything decent for ages, it’s because we’ve been planning our wedding, which finally happened on Saturday (May 29th, 2010). I thought I’d put a couple of photos on here today because a few of you seem to actually give a shit, and also then there’s less chance of me forgetting any future anniversaries.

If you've ever had a decent night out in Birmingham, you may recognise that as The Custard Factory

During the ceremony

Us in some "arty" doorway

Also, since I’ve still not written a Music On Drugs post, you might like to give some of the music we used in the ceremony a listen. Links to YouTube open in a new tab/window.

Before The Ceremony:

Jo Walking Up The Aisle:

Zero 7 – Pop Art Blue

Signing The Register:

Us Walking Out:

Lamb – Gorecki (started at 2:27)

Secular weddings are awesome!

(Image credit: Photos of my Wedding).

Posted in Personal | Tagged music, photos, wedding |

Science Joke Winners

Everyone’s a winner who entered last weeks Science Joke Competition! Not in the sense that everyone wins a prize, but in the sense that maybe, just maybe, we’ve inspired someone, somewhere to do something vaguely scientific. So who did win a prize? …

The Winner

Potter

There is this farmer who is having problems with his chickens. All of the sudden, they are all getting very sick and he doesn’t know what is wrong with them. After trying all conventional means, he calls a biologist, a chemist, and a physicist to see if they can figure out what is wrong. So the biologist looks at the chickens, examines them a bit, and says he has no clue what could be wrong with them. Then the chemist takes some tests and makes some measurements, but he can’t come to any conclusions either. So the physicist tries. He stands there and looks at the chickens for a long time without touching them or anything. Then all of the sudden he starts scribbling away in a notebook. Finally, after several gruesome calculations, he exclaims, ‘I’ve got it! But it only works for spherical chickens in a vacuum.

The Runners Up

James

Wanted, dead AND alive: Schrödinger’s Cat

psiphi

Some helium floats into a bar, the bartender says “We don’t serve helium in here.”

The helium doesn’t react.

Fantastic! Remember though, if you’re not from the UK and you want to claim your prize, you’ll have to send us a couple of quid to cover the postage. We’ll sort all that out later. I’ll be in touch soon, probably, although we are getting married in 6 days, so there might be a bit of a delay… :^|

I’ve got to go and write my speech now, so I’ll leave you with this brilliant sketch from That Mitchell & Webb Look:

.

Posted in Competitions | Tagged blue lagoon, competition, entheogens, legal highs, mexican dream herb |

Science-Based Quick Competition

Following some rather depressing blog comments, I reckon it’s about time we had another competition in the name of science!

What Can You Win?

Blue LagoonBlue Lagoon

The winner will get a super awesome double size bottle of Blue Lagoon, a new liquid herbal high, and a 10g bag of Mexican Dream Herb. The two runners up will just get the Dream Herb.

What Do You Have To Do?

I want to hear the best science joke you’ve got. There’s a few to get you started at the end of this post. Obviously, I don’t expect you to write some new comedy gold, but at least have the decency to tell a joke in your own words and not just lift it from the first google result for “science joeks lol”. Post your entries in the comments below this post!

Who Can Enter?

If you’re in the UK, this competition is for you. If you live anywhere else, you can still win the stuff, just as long as you’re willing to PayPal me the postage costs. Usual rules apply, like being over 18, not mentally unstable or pregnant.

When Will The Winners Be Picked?

Over the next weekend probably. Who knows when exactly… depends when I’ve got 5 minutes. Get off my case already! Jeez..

Posted in Drugs | Tagged blue lagoon, competition, entheogens, legal highs, mexican dream herb |

Synthetic Cannabinoid Discussion

Drugs Discussion


UPDATE: This thread is now closed. Please continue the discussion here: Synthetic Cannabinoid Discussion II

This post is now the place to comment on the JWH-018 Toxicology article.

Not that there are any points, but bonus points for backing up what you say with peer reviewed research. Please keep the discussion scientific. You can talk about dodgy vendors if you must, especially if there’s a bad batch going round, but please don’t link to them or turn this into a customer support thread. If you want to talk about individual smoking mixtures, please do so Here.

Ok, go:.

Posted in Pharmacology | Tagged binding affinities, cannabinoid receptors, JWH-018, jwh-073, synthetic cannabinoids, toxicology |

Smoking Mix Discussion

Drugs Discussion

I’m creating this post so you lot can discuss smoking mixtures. Feel free to talk about the pros and cons of different individual products, but don’t talk about the vendors themselves. Comments like ‘This shiz I got from buydrugslmao.com is suhweeet” will be deleted.

Ok, go:.

Posted in Drugs | Tagged discussion, smoking mixtures |

How To Make A Bomb

No, this post won’t be a detailed guide to clandestine hexamethylene triperoxide diamine manufacture, sorry! Instead of terrorism, today’s post will focus on a great harm reduction technique called bombing (or parachuting for us in the far-less-extreme UK).

The Problem:

You have a bag of a drugs. That bag of drugs can be snorted, or it can be eaten.  Unfortunately, your nose wasn’t meant for hoovering up monster lines of chemical. Apart from the physical irritation to your delicate mucous membranes, vasoconstrictive drugs like cocaine or mephedrone will restrict bloodflow in the vessels lining your nose, which could lead to ischaemia, or the damage of tissue as a result of poor blood perfusion. If that wasn’t bad enough, pretty soon, your nose might start pouring with snot or just feel bunged up when the drug wears off, as the blood vessels open back up to compensate – your nose isn’t blocked with snot or drugs necessarily, but by these vessels filling up with blood, which closes off your nostrils, making it harder to breath.

Suppose at this point, you still have most of your massive bag of drugs left – what do you do? Perhaps the most instinctive thing to do is reach for something to unblock your nose, such as a decongestant spray or some “Vaporub” type stuff, so you can continue your hedonistic nasally-orientated pleasure-binge. It might surprise you to learn that this won’t help out your stinging nostrils as much as you think. These kind of products work by constricting those same blood vessels that were constricted earlier, adding to the ischaemia. If that wasn’t enough, continued use of these kinds of products could give you rebound congestion – as soon as you stop using them, your vessels open back up to compensate and before you know it, you’re adding an extra “b” to every word you say ended with a bilabial phone.

That’s just the physical side of things. Snorting drugs does get them into your blood faster, sure, but this also makes whatever you’re snorting more addictive. With our old friend mephedrone, snorting certainly can be fun, but it’s much easier to have “just one more line” another ten times in the same session than if you ate it.

The Solution:

If your bag of drugs also works well when eaten, eat that shit! Obviously no one wants to be chucking fistfulls of disgusting powder into their mouths, which is where our friend the bomb comes into play.

Step 1: Get Your Shit Together


You will need:

  • Rizlas (or whatever brand of rolling paper is most prevalent where you’re from)
  • A bag of drugs
  • Something to transfer the drugs from the bag to the papers

Step 2: Take A Single Paper

Step 3: Tear Off The Excess


You don’t need much, probably about an inch or so.

Step 4: Transfer Your Drugs To The Paper


Safety first! If your drug of choice requires only a few miligrams, or you’re generally unsure how to eyeball a dose, weigh it out first, then transfer it to the paper.

Step 5: Pick Up The Paper


Get the paper to fold naturally, as though you’re about to roll the world’s tiniest joint packed with chemicals.

Step 6: Pinch The Paper


Pinch one end of the paper, so you can hold it at an angle and tap the powder into the pinched end.

Step 7: Pinch T’Other Side


Repeat step 6 with the other side, so the powder takes up as little room as possible.

Step 8: Pinch Both Sides


This step should get your little pile of drugs in the centre of your paper. Don’t be afraid to compress it a little so it stays in place. The last thing you want is stray drugs working themselves free and onto your taste buds.

Step 9: Begin To Form A Tail


No, don’t actually grow a tail. Just pull together the pinched ends of the paper, so the drugs are at one end and the free bits are together at the other.

Step 10: Form A Tail


Pinch all the excess paper into one clump between your thumb and finger.

Step 11: Complete The Tail


Now roll the tail betwixt your thumb and finger to tighten it. Feel free to lick your fingers first to help it seal, but not too much, or you’ll be left with a wet powdery mess.

Step 12: Marvel At Your Creation


Now it’s time to stick it to the infidel! Erm, I mean, take your drugs safely.

Nice work!

(Pictures provided by methuselah969).

Posted in Teks | Tagged bombing, harm reduction, parachuting |

Mephedrone Banned On Friday 16th April

Following the ACMD’s report on the cathinone derivatives (Part I & Part II), here is the latest amendment to the Misuse of Drugs Act to control them:

Dangerous Drugs, England And Wales
Dangerous Drugs, Scotland
The Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2010

Made
31st March 2010

Laid before Parliament
1st April 2010

Coming into force
16th April 2010

The Secretary of State makes the following Regulations in exercise of the powers conferred by sections 7, 10, 22 and 31 of the Misuse of Drugs Act 1971(1).

In accordance with section 31(3) of that Act the Secretary of State has consulted with the Advisory Council on the Misuse of Drugs.
Citation, commencement, interpretation and extent

1.—(1) These Regulations may be cited as the Misuse of Drugs (Amendment) (England, Wales and Scotland) Regulations 2010 and shall come into force on 16th April 2010.

(2) In these Regulations “the 2001 Regulations” means the Misuse of Drugs Regulations 2001(2).

(3) These Regulations extend to England, Wales and Scotland.
Amendment to the 2001 Regulations

2. The 2001 Regulations shall be amended as follows.

3. In Schedule 1 (which specifies controlled drugs subject to the requirements of regulations 14, 15, 16, 18, 19, 20, 23, 26 and 27)—

(a) in paragraph 1(a), after “methcathinone”, insert—

“4–methylmethcathinone”;

(b) after paragraph 1(l), insert—

“(m) Any compound (not being bupropion, diethylpropion, pyrovalerone or a compound for the time being specified in sub–paragraph (a) above) structurally derived from 2–amino–1–phenyl–1–propanone by modification in any of the following ways, that is to say—

(i) by substitution in the phenyl ring to any extent with alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents, whether or not further substituted in the phenyl ring by one or more other univalent substituents;

(ii) by substitution at the 3–position with an alkyl substituent;

(iii) by substitution at the nitrogen atom with alkyl or dialkyl groups, or by inclusion of the nitrogen atom in a cyclic structure.”.

David Hanson
Minister of State
Home Office
31st March 2010

Let’s take a look at this and try and make some sense of it shall we?

(a) in paragraph 1(a), after “methcathinone”, insert—

“4–methylmethcathinone”;

First off, mephedrone (4-methylmethcathinone) is explicitly mentioned to appear after methcathinone, which is already class B. I suppose we knew that much was going to happen already, so onto the more complicated stuff…

(b) after paragraph 1(l), insert—

“(m) Any compound (not being bupropion, diethylpropion, pyrovalerone or a compound for the time being specified in sub–paragraph (a) above) structurally derived from 2–amino–1–phenyl–1–propanone by modification in any of the following ways, that is to say—

This means that any cathinone derivative described by any of the following paragraphs will also become class B. Like the cannabinoids banned last December, this ban doesn’t list a tonne of individual substances, but instead covers a wide range of actual and theoretical substances by detailing possible alterations to the original cathinone structure. Here they are:

(i) by substitution in the phenyl ring to any extent with alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents, whether or not further substituted in the phenyl ring by one or more other univalent substituents;

This first part covers modifications of the phenyl ring, or “round bit” of the cathinone structure (R4). Unfortunately, this covers a massive range of compounds, including Mephedrone (alkyl), Methedrone (alkoxy), Methylone, Ethylone, Butylone & MDPV (all alkylenedioxy) and flephedrone (halide; also includes the 3-F isomer) .

(ii) by substitution at the 3–position with an alkyl substituent;

This covers the addition of a carbon side chain of any length on the carbon atom just before the nitrogen atom (usually referred to as the alpha carbon).  All the compounds listed in Annex A,  Appendix 1 of the ACMD’s report include a chain of at least one carbon long (alpha methylation), but by not specifying the length of this “alkyl substitute”, this also covers  existing compounds with longer alpha side chains such as pentylone and MDPV as well as any potentially interesting theoretical compounds.

(iii) by substitution at the nitrogen atom with alkyl or dialkyl groups, or by inclusion of the nitrogen atom in a cyclic structure.”

The final nitrogen atom present in cathinone has two available places to add stuff. One or both of these could be a carbon chain (alkyl or dialkyl), or a single carbon chain could form a ring by starting and ending at this nitrogen atom (the “cyclic structure”), which is what this part covers. Examples include ethcathinone (alkyl – a single carbon chain), n,n-dimethylcathinone (dialkyl – two carbon chains) and MDPV (includes the cyclic pyrrolidinyl structure).

I know that’s still quite technical, but hopefully what I’ve written is a little clearer than the original text. Feel free to ask questions in the comments though!

The gist is, all the popular cathinone derivatives mentioned by name above will become class B on Friday 16th, as well as a great deal of the more esoteric ones. One compound not included in this ban is naphyrone, currently marketed as Energy-1 or NRG-1. Unfortunately, I hear it’s rather shit and also not particularly safe, but the ACMD are already looking into banning that for next time. That’s pretty much it for cathinones in the UK then. I feel like we should all go out and get commemorative T-shirts or something… 🙁

On a more serious note, for those previously law abiding citizens who have developed a psychological addiction to mephedrone, you have two choices: continue buying lower quality stuff at an inflated price from a regular drug dealer or find some help. Luckily, Drug-Forum.com has a great Recovery and Addiction section that you should definitely check out.  You’re also welcome to post your stories and progress in the comments under this post..

Posted in Legislation | Tagged ACMD, addiction, butylone, cathinone, classification, dimethylcathinone, energy-1, ephedrone, mdpv, mephedrone, methylone, naphyrone, nrg-1, pentylone |