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5% Discount on Legal Highs, Salvia Divinorum and Everything Else From The Coffeesh0p

Coffeesh0p Changes

Coffeesh0p has gotten bigger and bigger over the past couple of years, stocking more and herbal highs, entheo­gens, pipes, bongs, etc. Deciding where it all goes is now more important than ever. Organ­ising the product cat­egories — the virtual floor plan — is increas­ingly important for both ease of access and intu­itive shop­ping, as well as optim­isa­tion with the search engines. I think it’s about time for a big reshuffle!

Ini­tially, Salvia Divinorum was the only cat­egory in the sh0p, since I made my own extract, but since then we’ve added tonnes more. The next were prob­ably the Legal Pills and Entheo­gens cat­egories. Here was the first problem — Salvia Divinorum IS an entheogen, so where the hell do I put it? Since then, I’ve always had Salvia in it’s own top-​​level cat­egory, as that’s always been our product of choice. The majority of vis­itors come looking for salvia, and the Salvia cat­egory, being a top-​​level cat­egory, always does well in the search engines. I’ve always been scared to move it to it’s rightful place within Entheo­gens in case it sud­denly dropped out of the search results and I had to get another job for a bit.

But now, we sell a lot of stuff! Cur­rently, we still have a top-​​level Salvia Cat­egory, along with Entheo­gens & Herbal Highs and Legal Pills. There are more, but these are the three I’m thinking of shuff­ling up a bit. When these cat­egories first started out, I wanted to keep everything in tablets in it’s own cat­egory and any­thing herbal in the Entheo­gens & Herbal Highs cat­egory, regard­less of what it was. We now stock various popular smoking mix­tures, many of whom don’t list their ingredi­ents so are argu­ably herbal, along with a number of entheo­gens, like Guarana, that I wouldn’t neces­sarily call a herbal high. We also have a rather out of place Snuff cat­egory, putting herbal Kanna side by side with Snow Blow herbal cocaine.

So, this has been getting at me more and more recently. Also, it might piss off some of the serious herb­al­ists, who get per­son­ally offended to see their entheogen of choice listed as a herbal high, but that’s not all. When I started Coffeesh0p, I had no idea about SEO, keyword research or any­thing else in that field. I figured “hmm, herbal highs sounds like a cool cat­egory name”. It turns out, that phrase, while cool, does not get a lot of searches com­pared to “Legal Highs”. A big reshuffle now might result in more traffic for this search term.

So, here’s what I’ll do. Raw herbs on their own will go into a new Entheo­gens cat­egory, including Salvia. Any­thing more recre­ational, like Spice smoking mix, Snow Blow and all of the legal pills section will go under a new Legal Highs cat­egory. Thrilling, I know!

But here’s the fun part. I decided it would be a good time to funk up the front page some­what. Maybe remove those massive ads in place a bit more colour for each cat­egory. Here are a couple of new banners I’ve been playing round with this afternoon.

Yes, I did painstak­ingly lay out all of those herbs, then sep­arate them all again at the end.

One more tip incase you ever need to change your website archi­tec­ture — make sure you cor­rectly redirect your old URLs to the new ones. The best way I’ve found is to use 301 redir­ects with the .htac­cess file, or make sure your cat­egories and products “know” where they’re sup­posed to be, and if they get called any­where else, they can 301 redirect them­selves to the proper loc­a­tion. The 301 redirect tells the search engines this is a per­manent relo­ca­tion, and so any benefit received from links pointing to your old pages will carry over the new ones.

Posted in Internet Marketing | Tagged coffeesh0p, seo |

Growing Salvia with Science

What better way to skim over the sci­entific method than by talking about Salvia Divinorum!

Bman_​666, over at Salvia­Source, had the very noble idea of applying a little science to growing salvia divinorum in order to dispel any myths or mis­con­cep­tions about it, and maybe produce the ulti­mate “How To Grow Salvia” guide for salvia cul­tiv­ators around the world.

Some of the vari­ables under scru­tiny are:

  • Natural vs arti­fi­cial light
  • Dif­ferent soil com­pos­i­tions /​ Fer­til­izer mixtures
  • Effect­ive­ness of CO2 supplements
  • Con­tained growing (with con­trolled humidity) vs growing out in the open
  • Will your TV kill your plant? [What?! — I suppose most sci­entific break­throughs develop from “outside-​​the-​​box” thinking, so I’ll reserve judgement…]
  • Hydro­ponics vs Soil
  • Watering fre­quency
  • Misting the leaves vs not
  • Varying soil pH
  • Distilled/​bottled/​tap water comparisons

Noble goals indeed, but at the time of writing, Bman_​666 wasn’t quite sure what he’d be letting himself in for! The first page of the thread in ques­tion con­tained some excel­lent insight about how the results might be struc­tured within the forum, and some quick guidelines on stand­ard­isa­tion, which are both important to prevent con­fu­sion and help mine accurate data. But there was one thing missing — repe­ti­tion, they key to any sci­entific study.

Perhaps they’re way ahead of me, I thought — we could all take repe­ti­tion for granted. Just to be extra vigilant (the, uhh, second key to any sci­entific study? It must some kind of many-​​keyed com­bin­a­tion lock, with iris scan­ners ‘n’ all. A com­plic­ated beast!), I posted my advice on using 8 – 10 plants per vari­able to test. So, 4 – 5 plants for the control and another 4 – 5 dif­fering in a single respect (ie, watered with deion­ised water). It turns out they weren’t as far ahead as I thought.

At this point, I’ll just point out I had to explain the same thing to someone in the lab today. We were setting up cell cul­tures in order to add varying con­cen­tra­tions of a drug (ret­inoic acid) to them to see what happens. For each con­cen­tra­tion of the drug (dis­solved in a solvent), we had a total of 8 cell cul­tures set up — 4 to receive the drug/​solvent and 4 to receive the solvent without the drug, as a control. Since the concept of repe­ti­tion seemed a less uni­versal concept than I first real­ised, I figured I’d talk about it here.

So, back to this thread. My reply was the following:

Suppose your get set up with your soil cutting and your hydro cutting. If, for some unknown reason, the hydro cutting dies, all you can con­clude is that hydro kills salvia plants.

Or, say in 1 week your hydro plant grows 10cm and your soil plant grows 9cm (I have no idea how fast it grows; figures are arbit­rary). All you could con­clude from that is that plants that grow in soil grow 90% as well as those with a hydro setup. Now, sup­posing you had 5 plants with each vari­able — the hydro plants grew this much {10,12,16,17,23} (average 15.6cm) and the soil plants grew by this much {5,7,8,8,9} (average 7.4) — as you can see this data sug­gests an approx 50% dif­fer­ence. Taking the tallest/​shortest com­bin­a­tions of your 5 plants, you could end up with a height dif­fer­ence of as much as 18cm or as little as 1cm — working with only 1 plant per vari­able can give you very inac­curate data.

In reality, the ranges will likely be much nar­rower, but you should get the point. Even plants grown under identical con­di­tions will not develop 100% identic­ally, and that vari­able is one that you need to take into account, like any other (eg humidity). Because you can’t control that vari­able, the best you can do is elim­inate its effects by using mul­tiple data and aver­aging. You wouldn’t trust a drug that had been tested on a single indi­vidual, would you?

I hope that can high­light just how metic­u­lous you have to be with your research. Growing only two plants side by side is great for a fun, per­sonal exper­i­ment, but to further the col­lective know­ledge in a par­tic­ular field, you need to apply a strict sci­entific method.

Bman_666’s main concern with repe­ti­tion was the number of plants he had avail­able, which is fair enough. But serious science demands a serious com­mit­ment. From an idea in the mind of a chemist, to an actual pre­scrib­able drug, phar­ma­ceuit­ical com­panies have to spend hun­dreds of mil­lions of dollars on research, involving trials of thou­sands of people.

While the details may be a bit out, the Salvia­Source guys are cer­tainly making tracks in the right dir­ec­tion. If you have 10 or so salvia clones lying around, maybe you can con­tribute to this fas­cin­ating project? Be sure to get involved @ Salvia­Source!

Posted in Drugs | Tagged growing, salvia divinorum, science |

More Shoddy Journalism

Happy Caps X-EHypnotic PillsSpace Cadets

[This is the first post by my girl­friend and Coffeesh0p partner Mrs_​Synch!]

What’s wrong with this article?

We can all debate until we’re blue in the face about alcohol, drugs, their legal altern­at­ives, tobacco and whatever else is a source of con­tro­versy in this country. My problem with this article, however, is not that I dis­agree with the journalist’s point of view (although I do). It’s that if this is what counts as journ­alism these days (on the BBC news website no less!) I am, quite frankly, shocked and dis­ap­pointed. These are some of the reasons I felt so strongly about it (I’ll address each point in the order they come in the article):

  1. ‘The pills or liquid’ — what? How vague is this? I know it’s only the second para­graph but read on and the trend con­tinues. There are no names of the brands, retailers or whole­salers they are refer­ring to. They mention none of the ingredi­ents they claim are so dan­gerous apart from this delib­er­ately con­tro­ver­sial ref­er­ence to BZP. As a herbal highs retailer in the UK, I can per­son­ally say that I know of no whole­salers that are willing to sell us any products con­taining BZP. Although the legal status of BZP does seem to be a bit dodgy (the article said it becomes illegal in March, but I’m pretty sure it’s tightly con­trolled here already), as far as herbal high sellers go BZP is not readily avail­able in the UK. It is cer­tainly not ‘one of the main ingredi­ents in many products’ in the industry. This is quite simply a lie, and a demon­stra­tion of the lack of research done on the part of the journ­alist. Ten minutes on Google could have told her this is not the case.
  2. ‘Twenty-​​five-​​year-​​old Alex from Birm­ingham’ — Right, I see. So the whole sub­stance of this piece comes from a girl who got pissed, took EIGHT uniden­ti­fied legal pills, slept in a field all weekend and then got the shits. Come on BBC, this is really poor. The symp­toms Alex lists are also, incid­ent­ally, ones you can expect from your common or garden hangover. Admit­tedly the guy who sold her the pills was obvi­ously an idiot, but you get a great many idiots in bars who con­tinue to serve people who are so drunk they can barely stand up. I have also never seen a pack of legal pills which do not expli­citly carry the warning ‘Do not drink’, and by her own admis­sion she and her friends were already drunk.
  3. “These things are packets of tablets and cap­sules sold as herbal highs, but are in no way herbal. These things are purely syn­thetic chem­icals,” he said. — Yes, this is a quote from a doctor so it seems almost cred­ible, but again, the vague­ness of this point just makes it stupid. Yes, I’m sure there are pills out there that are advert­ised as herbal and aren’t. But cer­tainly not all of them, and there are a large number of reput­able retailers out there who actu­ally do give a shit about the safety of what they sell. There is one very obvious example of legal pills that ARE undeni­ably entirely herbal, and that’s Happy Caps. If this journ­alist had done her research, she would have found out in minutes that Happy Caps are cap­sules, not tablets (so not even any harm­less tab­let­ting agents), and that they contain ground up herbs and extracts. Hell, you can SEE what’s inside them if you pull the gel cap apart, and it’s planty and quite def­in­itely herbal.

Whilst this journ­alist clearly has an agenda (read: drugs are bad), this poorly written piece of tripe has given me no inform­a­tion what­so­ever. I’m always inter­ested to hear someone else’s point of view, and when I saw the title, was excited about reading it and pos­sibly reporting on it for Coffeesh0p. Unfor­tu­nately, I was left dis­ap­pointed in both this journ­alist and the standard of reporting that is obvi­ously pub­lish­able these days. BBC news editors, you should be ashamed of yourselves!

Posted in Drugs | Tagged herbal highs, media |

Salvia Divinorum is NOT like LSD!

Arrrghhh! We’ve all seen the media’s sen­sa­tion­alist take on Salvia Divinorum. I swear I’ve seen it men­tioned as “the next LSDand “the next marijuana” in the SAME article before. I’m sure it makes com­pel­ling reading for those con­ser­vative types, wielding the banning stick, but come on!

Just yes­terday, I received a news­paper clip­ping through the post entitled “Concern over craze for ‘psycho sage’ videos”. The article focused mainly on those tw@s that think it’s fun to post videos of them­selves on YouTube smoking salvia, which is fair enough, but in approx­im­ately 250 words of ill-​​informed “journ­alism”, I can see LSD men­tioned twice.

Salvia != LSD

Why This Is Fucking Stupid

  1. Any­thing labelled so con­sist­ently as “LSD-​​Like” is sure to receive a banning from any MP wanting to appear “tough on drugs”. We all know how Gordon Brown likes to ignore sci­entific evid­ence when it comes to drugs, so I don’t think the fact that salvia divinorum is NOTHING like LSD will be men­tioned at all. Con­sid­ering that this amazing herb does actu­ally have a lot of medi­cinal poten­tial, is it really worth com­paring it to LSD just to make exciting reading? This is a sure fire way to get it banned. Arse­hole Journ­alist: I’m sure all those people with Parkinson’s will thank you! (NB: that’s not to say LSD doesn’t have any clin­ical use — in fact, it shows amazing poten­tial in curing addic­tion far quicker than regular therapy — shame no one wants to research it any more because it’s such a bal­lache to get permission…)
  2. The public tends to believe it, and may get hurt! If that many places are reporting its sim­il­arity to LSD, then the unin­formed public will take it as read. Last night, someone sub­mitted an anonymous report on Salvia Trip, entitled “Not for me”. This bloke is a 36 year old pro­grammer, who used to be into LSD back in the good old days. He goes on to say that he’s heard about salvia and wanted a similar exper­i­ence. As you’d expect, he didn’t enjoy it. Thank­fully, nothing bad happened, but there is cer­tainly the poten­tial for some­thing to go wrong. This is only one report (and the inspir­a­tion behind this post), so imagine how many more people this has happened to. This piss-​​poor excuse for a journ­alist is going to do more harm than good.
Posted in Drugs | Tagged lsd, media, salvia divinorum |

Egyptian Ecstasy - Blue Lotus

Blue Lotus

The Egyp­tian Blue Lotus, Nymphaea caerulea, (also known as any com­bin­a­tion of Egyp­tian, sacred, blue, lily or lotus), has been called the ancient Egyp­tian equi­valent of ecstasy, but it’s psy­cho­active prop­er­ties have only recently been (re)descovered. In an inspiring piece of shocking journ­alism, com­bined with insane pho­toshop skillz, I, Syn­chronium, and my trusty girl­friend find out what all this fuss is about.

Look at that image again. That same white/​blue flower in each painting is what I’m talking about. It appears all over the place in Egyp­tian artwork, and now it seems it was the plant’s psy­cho­active prop­er­ties that made it so popular to the Egyp­tians. It seems we still know very little about this inter­esting plant, however. Both the Wiki­pedia and Erowid entries say next to nothing, par­tic­u­larly on the phar­ma­co­lo­gical aspects. I’m cur­rently waiting for someone on Spir­it­Garden forums to get back to me about a rather more com­pre­hensive paper he found which focuses on the chem­istry — the only problem is, it’s not in English. :-/​ More updates on that later, I hope. All I’ve gathered so far is it con­tains nuci­ferine and apo­morphine, a dopamine agonist.

So, the only piece of inter­esting inform­a­tion about the plant is from the 50 minute long doc­u­mentary Sacred Weeds — Blue Lily. This came out in 1998, so the only copy I found isn’t great quality. It’s totally worth a watch, though, so I’ve included it at the end of this post. Wiki­pedia has the fol­lowing to say:

The series ended with the invest­ig­a­tion of the psy­cho­active effects of the Blue Lily (Nymphaea caerulea), a sacred plant in ancient Egypt. Michael Car­mi­chael [hah!] sug­gested that the psy­cho­active effects of the blue lily and other psy­cho­active plants estab­lished a new found­a­tion for under­standing the origins of philo­sophy and reli­gion in ancient Egypt. Alan Lloyd, the ranking took a more cau­tious approach. After wit­nessing the effects of the plant in two volun­teers, all parties agreed that it was a psy­cho­active plant. Sher­ratt accepted the new paradigm for the origins of ancient philo­sophy and reli­gion in his sum­ma­tion of the series.

Only one avenue remained unturned — trying it ourselves. Someone’s got to do these things, right?

Method - Two People

Rosé wine
Take one bottle of generic £7 rosé wine and 25g dried blue lotus. Uncork the wine and pour your­self a little bit — if you don’t, the plant material won’t fit into the bottle. If you haven’t worked it out by now, the next step is put the plant material in the bottle. Then re-​​cork, shake a bit, and put back in the fridge. In about three days (yes, three days; serious journ­alism and sci­entific research need to be planned in advance!), your wine should have taken on a much darker hue.

When the time comes, you first need to filter the wine. Generic coffee filters are great for this, but you can use a clean tea towel too. Just pour your wine into a filter slowly until only soggy lotus flowers remain in the bottle. I found the best way to get these out was a long pointy thing and lots of patience. As they come out one by one, put them in a sieve over a jug of some descrip­tion. Once you’ve got them all out, press them into the sieve to get as much wine out as pos­sible. Once it’s all filtered, rinse out your wine bottle and put the wine, sans flowers, back in the bottle for storage. Drink the bottle between two people in the space of about one to two hours. On Sacred Weeds, they also ate the flowers when they real­ised they had no more wine left. Bear in mind that they had to import these fresh from Egypt at the time, so I think I’d have done the same! You can totally eat the once-​​dried flowers that you can buy today, but they won’t be a nice as the fresh flowers. Just like Guarana, this is one of those plants that actu­ally tastes pretty nice.

Results

The wine taste alright. It’s more bitter than usual, as you’d expect, but nothing like dream herb or kratom tea. It’s easy enough to knock back, but if you’re a big girl, you can mix it half and half with lem­onade. The effects of the lotus itself come about at the same time as the alcohol — about 10 – 15 minutes after drinking. The effects are subtle and enjoy­able, getting more pro­nounced the more you drink. Relax­a­tion is the first thing you’ll notice, as well as a more talk­ative demeanour. Things seem more amusing and perhaps a little more enjoy­able. You will def­in­itely adopt a more cheerful disposition!

I don’t know if it was the lotus, or if I was just knackered after a long day, but by about mid­night, I was falling asleep with my clothes on. More invest­ig­a­tion is neces­sary before con­clu­sions can be drawn!

Conclusion Blue Lotus
Pros:

  • Easy to prepare
  • Feels great
  • Tastes pretty nice

Cons:

  • It's quite pricey @ £8 per person.
  • It takes a while to soak

There's not a lot more to say, really. I wouldn't say the lotus made me ecstatic, but for an ancient herbal equivalent, it's not half bad. This is definitely a plant I'd try again, and recommend to others.

Sacred Weeds

As promised, here is the Sacred Weeds - Blue Lily episode. Sit back, relax and enjoy!

In other news, I'll be launching some competitions soon, so keep an eye out for chances to win loads of cool stuff.

Posted in Drugs | Tagged blue lotus, ecstasy, sacred weeds |

The ATA vs Jacqui Smith

Recently, everyone’s favourite Home Sec­retary, Jacqui Smith, set a few dis­turbing pro­posals to House of Commons, fol­lowing advice by the Advisory Council on the Misuse of Drugs (AMCD), regarding the sale of can­nabis seeds and smoking paraphernalia. Let’s have a little look, shall we?

The AMCD recom­mends investigating:

“whether it might be prac­tical to bring can­nabis seeds within the scope of the Misuse of Drugs Act”

and also recom­mends that:

“The Home Office should assess the extent to which the trade in can­nabis paraphernalia might be more effect­ively regulated”.

So wait, everyone ignores the AMCD unless they agree with your agenda? Bril­liant! As if stop­ping the sale of king-​​size rizlas will result in massive, country-​​wide decline in pot smoking, anyway…

Enter The ATA

Nat­ur­ally, this dick-​​move is a very unset­tling one for anyone that sells can­nabis seeds, or smoking paraphernalia, such as myself. Enter the ATA — the Altern­ative Trade Asso­ci­ation! They describe them­selves as a “coali­tion of UK whole­salers, attempting to stop these mis­guided pro­posals becoming law”. They not only provide you with a weath of inform­a­tion about the subject and how to keep your busi­ness safe (including updates about any future legis­lative changes), but they also have plenty of retained legal muscle to defend any action taken against the industry.

They’re also setting up a website, Smoke​-Aware​.co​.uk, to educate people on the risks of smoking and the prob­lems drug use can bring. On top of that, they’re also appar­ently plan­ning to launch some kind of media cam­paign, but I’m not too sure what that will involve.

For a start, it’s great to see people not lying back and taking this crap, so well done ATA! Let’s hope we can get everyone involved — surely there’s strength in numbers? With any luck, these ridicu­lous pro­posals will be nipped in the bud before our gov­ern­ment start looking any more stupid.

For any internet-​​marketing-​​savvy whole­salers out there, signing up gets you a search engine friendly, high quality link dir­ectly to your site. That can only help you in the search engines. On the down­side, they do require all members to link back to them, which auto­mat­ic­ally makes me some­what wary. But for all you get in return, one link back isn’t going to hurt. :-)

Update: It seems herbal highs are under threat as well. Current Gov­ern­ment: “Let’s ban everything until we know it’s safe” — I can hardly see them act­ively allowing the sale of any­thing, can you?

Posted in Internet Marketing, Legislation |

Salvia Trip

Today, I’m going to talk about my most recent project (apart from this blog), Salvia Trip. Salvia Trip

Back Story

Ori­gin­ally, most of the exper­i­ence reports came from Salvia­Source (in my mind, the number one salvia divinorum com­munity), but due to a decision by the owner (Para­doxic) to move away from the exper­i­ence and focus more on the cul­tiv­a­tion and the science behind it all, the reports were removed from the site. In a stroke of bene­volent wisdom, Para­doxic decided to compile all of the reports in both a Word doc­u­ment and SQL format. Seeing a massive cache of free, keyword-​​rich and rel­at­ively unique content, I jumped at the chance to down­load the lot, determ­ined to do some­thing worth­while with it.

Picking the Domain

Using Google’s free Keyword Research Tool, I played around with a few words including “salvia”, “divinorum”, “exper­i­ence” and “trip” in various com­bin­a­tions. It turns out the phrase “Salvia Trip” gets approx­im­ately 12,000 searches per month on Google, and with only 138,000 com­peting sites, some domain fea­turing the words “Salvia” and “Trip” was going to work best. Salvia​-Trip​.net and Salvia​-Trip​.com were both avail­able, so I registered both of them, and pointed .com to the .net extension.

Giving Something Back

When I was first tossing ideas around about what to do with these reports, my incent­ives were two-​​fold. Make a bit of money myself and give some­thing back to the salvia com­munity. Ini­tially, I had just wanted to create a place that the com­munity would be able to use and enjoy, while keeping any income from the site seperate. I had con­sidered a single “shop” page on the site through which to sell some salvia, but I thought that might be a bit tacky, and more likely to land me in hot water some­where down the line. So, I decided I’d put some adverts around the trip reports, and that’s when I real­ised I could combine both of my goals in a single elegant solu­tion —  give the members some of the advert­ising revenue! The user regis­tra­tion form now allows you to input your Adsense pub­lisher id, if you have one, so we can display adverts belonging to your own Adsense account 25% of the time.

Design

I wanted to keep it simple. Well, maybe I did. Maybe it’s also down to the fact that I totally suck at Pho­toshop. Whatever the reason, I knocked up a quick design and got things up and running as soon as pos­sible. My first real Pho­toshop attempt was designing the header — not bad, I reckon. In case you can’t tell, I did pretty much exactly the same thing for the header and rss button here.

Progress

So far, things seem to be going well. A few links have been exchanged and Salvia­Source now recom­mends all its users submit their trip there for comment. That’s got to be good, right? More import­antly though, how’s it doing in Google, the biggest, baddest search engine of them all? Well, it’s been up for little over a month now, and already we’re on the front page. No doubt I’ll talk about this site again in the future, so I’ll keep everyone up to date with it’s progress.

Anyone can submit their reports anonym­ously, or by cre­ating an account first. In the not-​​too-​​distant future, I might be giving away some salvia to the top members, who have con­trib­uted the most, so keep an eye out for that.

Posted in Drugs, Internet Marketing | Tagged keyword research, salvia divinorum, salvia trip |

Salvia Divinorum Presentation

Salvia Divinorum

Salvia Divinorum

It’s been a week now since I started back at uni­ver­sity, and everything’s going great — we’ve dived head first into my first module, Phar­ma­co­logy: from Molecules to Man. This com­prises of 25% course­work and a 75% exam right at the end. The course­work is further divided up into essays, lab write-​​ups and …a 10 minute present­a­tion on the topic of my choice! Right now, I’m pretty certain I’ll be talking about Salvia Divinorum, as it’s just plain more inter­esting than any­thing else, both for me to talk about for ten minutes and for everyone else to listen to it. Soooo, what to talk about for ten minutes?

Although this will be a serious phar­ma­co­lo­gical talk, I think I can get away with a bit of history of it’s use and what the plant rep­res­ented to the ancient civil­iz­a­tion that used it. If anyone has any inter­esting facts, now’s the time to share them! But what about the serious phar­ma­co­logy stuff? Well, these papers are pretty good.

The first talks about the extremely selective action of Salvinorin-​​A on kappa opioid receptors. The

Salvinorin-A

Salvinorin-​​A

hal­lu­cino­genic prop­er­ties of this com­pound, medi­ated by activ­a­tion of these receptors could be useful clin­ic­ally. If activ­a­tion of these receptors is capable of bringing about hal­lu­cin­a­tions, turning them off (with a selective ant­ag­onist) could help dis­eases in which hal­lu­cin­a­tions are prom­enant, such as Alzheimer’s and schizophrenia.

The second paper is much more easy going. This one focuses on the method of absorp­tion and its effect on the exper­i­ence. By com­paring what happens when the com­pound is vapor­ised and inhaled, absorbed sub­lin­gually (under the tongue) and eaten, it proves that absorp­tion through the gut has little or no effect.

But what else is there to talk about? Any other papers worth a read? I might write up a tran­script of the present­a­tion here, along with the Power­Point present­a­tion itself.

Posted in Pharmacology | Tagged salvia divinorum |

Guarana In My Coffee

I don’t know about you, but I am not a morning person. Every day, my alarm goes off. Every day, I hit “Snooze” at least five times. The worst parts of my day are a) the 30 second count­down before I tell myself I have to actu­ally get out of bed, b) the approach to the bath­room, anti­cip­ating the sub-​​zero tiles on the bath­room floor, c) turning the shower off and d) drying my hair — the moment I apply a towel, I can feel my icy hair sapping away any remaining warmth.

I get the feeling I’m the only person that cannot bear getting out of bed. At 9am, everyone else seems cheery; I’m feeling miser­able, trying to pry my eyes open. Some­times, I even feel deli­rious, just trying to force myself to stay awake. So, I decided to do some­thing about it.

This morning, I cracked open a tub of powdered Guarana, aka Paullinia cupana, a Brazilian herbal stim­u­lant, and added a teaspoon-​​full to my coffee. This is one of those (seem­ingly rare) herbs that actu­ally tastes nice as well as pos­sessing psy­cho­active prop­er­ties. Right now, at 9:51, I’m wide awake and not too bothered that it’s another 15 hours before I’m asleep once more. I’m just praying the effects won’t wear off and leave me in an unsus­pecting heap on the lab floor.Powdered Guarana

One thing to look out for with Guarana is making sure you stir your coffee prop­erly. If you don’t, the last dregs are full of powdery chunks, but it’s not the end of the world. Did I mention that this actu­ally tastes pleasant?

Guar­anine, the com­pound respons­ible for keeping my eyes open, is chem­ic­ally identical to caf­feine, derived from other sources, but that leaves out the plant’s other xanthine alkal­oids, such as theo­bromine and theo­phyl­line. These stim­u­late the heart, among other things, so it def­in­itely gets you going.

If Guarana really is this good, I think I’ll be using it every day. My quality of life has just increased dramatically!

Posted in Drugs | Tagged guarana |

Good News From Google

…For me, anyway! This quarter’s toolbar PageRank update has been a good one.

Coffeesh0p has gone from 2 to 3, with all my main cat­egories having a PageRank of at least 1
Salvia Trip has gone from 0 to 2
A-​​muscaria & P-​​viridis have both gone from 0 to 1

PageRank

For those that don’t know what PageRank is, it is one of many metrics that Google uses to rate your site, and is gen­er­ally determ­ined by the links to your site from other pages. If one page has a high PageRank itself and links out to only a few other sites, more of that “Link Juice” is going to flow down each of those links. If a page has a low, or non-​​existant PageRank and links to many sites, those links won’t pass as much juice. It’s these links to your site, or back­links, as they’re known in the industry, that govern where you appear in Google’s search results. Relevent sites, with high PageRank that link back to your own site can really provide you with a boost in rankings.

Remember, PageRank is only one factor that Google uses when thinking about your site. As a general rule, pages with a higher PageRank should be more trust­worthey than those without. Having little or no PageRank is a good indictor that a site is new, or doesn’t get a lot of traffic. You can see the PageRank of any site you visit by installing the Google Toolbar.

Posted in Internet Marketing | Tagged google, pagerank, seo |