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Mephedrone: The Facts

I don’t know how much people outside “the industry” have heard about mephed­rone, but by all accounts, it’s exploded in pop­ularity over the past few months. In the last three months, there’s been at least 50 news stories reposted to Drugs-​​Forum on the topic, and prob­ably quite a few more that haven’t been picked up. We’ve got reports of teens dying, 11 year olds taking the stuff and a guy ripping his balls off — all the classic examples of the media whip­ping up an unne­ces­sary (and untrue) shit storm. I’ve also read lots of anec­dotes about the drug’s pre­val­ence among stu­dents, friend­ship groups and even dealers of illegal drugs (points for diver­si­fic­a­tion!). Since my art­icles on JWH-​​018 have been reas­on­ably popular and stim­u­lated some inter­esting dis­cus­sion, I felt it was about time we gave mephed­rone the same treatment.

The Basics

Mephed­rone is not only cheap and legal, but it’s also incred­ibly effective. It’s a short-​​acting stim­u­lant that feels some­thing like a mixture of cocaine and ecstasy. If that wasn’t enough to explain its pop­ularity, then the icing on the cake is the almost com­plete lack of a comedown the next day when used in mod­er­a­tion. Pur­ities of over 99% make another great selling point when com­pared with similar illegal drugs.

Mephed­rone is a white, crys­tal­line powder with little to no smell. The term “Mephed­rone” comes from methyl–ephed­rone, describing the chem­ical struc­ture.  Other names for it include:Mephedrone Powder

  • 4-​​MethylMethCathinone (meth­cath­inone is another name for ephedrone)
  • 4-​​MMC
  • 4-​​MMCAT
  • MCAT (This is incor­rect, but people use it anyway)
  • Meow
  • Bubbles (seems to be a brand name for cap­sules con­taining it and methylone, another research chemical)

Effects include an initial euphoria, which tapers off to a milder stim­u­la­tion. Mephed­rone does seem to oil social situ­ations rather well and get everyone talking, laughing and having a good time, espe­cially during the initial euphoria. Several users have com­pared it to cocaine, but some how less jittery and “arrogant”, while others will compare it to a more rushy ecstasy (which has to be a good thing, given the current state of the MDMA market). Actu­ally, the effects seem to depend very much on dose and your chosen route of administration.

The most common ways to get this stuff into your blood are snorting it and eating it. As you can prob­ably imagine, eating it will give a longer, less intense exper­i­ence, while doing lines of it will give a much shorter, more intense buzz and make you want to keep taking it, but we’ll get to that later. Oh, I should prob­ably mention that snorting it feels not too dis­sim­ilar from being raped in the sinuses by a Por­tuguese Man o’ War, par­tic­u­larly for your first line.

Other reported methods of admin­is­tra­tion include shoving it up your arse, requiring less than an oral dose and peaking some­where between an oral or insuf­flated dose, and intra­ven­ously injecting it, which appar­ently isn’t that great, having a similar effect profile to being snorted with a million times the risk.

Dosage

A single oral dose would typ­ic­ally be between 150 mg and 300 mg, while lines can range from 50 mg to a monster 150 mg rail.

Pharmacology

MephedroneIf only we knew! Unfor­tu­nately, no one knows any­thing for certain, so we’re forced to do a bit of guess­work. If it feels like a cross between MDMA and cocaine, then we can assume that there’s some sero­tonin and dopamine involve­ment. The apparent addict­ive­ness of mephed­rone (more on that later, srsly), along with talk­at­ive­ness also points to dopamine path­ways, while the sim­il­arity of some side effects com­pared with sero­tonin deple­tion (taking too much MDMA or abruptly dis­con­tinuing selective sero­tonin reup­take inhib­itors [SSRIs]) points to the sero­tonin pathways.

I would love some more inform­a­tion on this, so if you ever come across any­thing in the future, please report back!

Misconceptions

There are a number of mis­con­cep­tions sur­rounding mephed­rone, which we should clear up:

Legal does not mean safe

While it seems that users can take vast quant­ities of the stuff and still func­tion,  we don’t know what the long term effects of mephed­rone use will entail. A handful of people have died from taking it too. While the number is tiny com­pared with alcohol, it’s still always a good thing to remember.

Purity isn’t neces­sarily accurate

Mephed­rone bought online will cer­tainly be purer than illegal drugs bought on the street, but claims of 99.9% purity may not be true. Since it’s not sold for human con­sump­tion (like everything legal and fun), I’m not sure an accurate purity measure is required. Also, that 0.01% could be some deadly poison. It prob­ably won’t be, but it might!

“Plant Food” might not be mephedrone

Lots of those news stories I’ve men­tioned above have listed a million dif­ferent “street names” for this drug, including “Plant Food”. No one is actu­ally calling it plant food, it’s just how it, and lots of other com­pounds like it, are sold. If you’ve obtained any­thing psy­cho­active pack­aged as plant food, make sure you know what the hell it is you’re taking!

Side Effects

Side effects can be many and varied, some serious and some not. Mephed­rone shares a number of the typical side effects you’d expect to find with any stim­u­lant, such as:

  • Increased heart rate (tachycardia)
  • Raised blood pres­sure (hypertension)
  • Not wanting to sleep (insomnia)
  • Not wanting to eat (anorexia)
  • Chewing/​grinding teeth (bruxism)
  • Moving your eyes loads (nystagmus)

More mephedrone-​​specific, and so perhaps more serious side effects include

  • Turning blue at the extremities & feeling cold (vasoconstriction)
  • Pains in the chest, throat and nose
  • Nosebleeds when snorted, espe­cially with pro­longed or fre­quent use

The more you use, the more the side effects become apparent and the initial pleasant effects diminish. Also, sig­ni­ficant evid­ence is coming forward sug­gesting cir­cu­la­tion issues are not just vaso­con­stric­tion, but some­thing more serious — autoim­mune vas­cu­litis, where the immune system attacks your own body. This would seem to account for some of the odd and infre­quent side effects, such as bruising or turning blue at the joints. Current reports suggest that this isn’t an issue of a dodgy supply for some people com­pared with the rest, but rather a small per­centage of the pop­u­la­tion are at risk, prob­ably because of some genetic dif­fer­ences. If you’ve noticed this, stop taking mephed­rone! This con­di­tion will only get worse the more you consume. Add to that the usual stimulant-​​induced vaso­con­stric­tion, and you could find your­self with some serious problems.

Warning

Mephed­rone can be addictive!

  • It’s easy to have several large ses­sions per week because of the cheapness and lack of comedown. Several people have reported taking over 20g per month.
  • It’s easy to keep taking it, espe­cially when snorted, so a single line can turn into 5g session easily if you lack self control. There have been a few reports of people taking 5-​​7g over a 48 hour long single session.
  • Tol­er­ance can also develop, so more is required for the same effect.

Safe Usage Tips

Mephed­rone is not 100% safe, but then again, nothing is. To make sure you’re as safe as pos­sible, here are a few tips:

  • Don’t buy it in bulk — 80% of people won’t be able to resist the charms of a massive bag of the stuff. Sure, you may save a few quid on the gram, but if your con­sump­tion sky-​​rockets, you’re not saving anything.
  • If you do buy in bulk, limit your­self — it’s all too easy to “just have one more line”, so perhaps let your friend look after your supply for you, or if you’re going out, take a pre­de­ter­mined quantity out with you and stick to it.
  • Don’t snort it if you think there’s any chance you will become addicted to it — this route of admin­is­tra­tion makes you want to keep on taking it much more than an oral dose, despite the snotty nose and watering eyes.
  • Eat healthily before and after — your body needs a good supply of nutri­ents, vit­amins, etc to stay healthy and replenish your neur­o­trans­mit­ters. Forcing your­self to eat, espe­cially during long binges, is essen­tial. At least munch some vitamin tablets or something.
  • Take some mag­nesium sup­ple­ments — this helps relax your muscles and stop all the jaw clenching and chewing that goes with most stimulants.
  • If you’re going to snort it, blow your nose soon after to clear out any powder — drugs aren’t  absorbed from your nos­trils, so you want to get rid of it. I’d also suggest giving your nose a wash with either a spray bottle and some water, or by cram­ming some wet tissue up there with your head tilted back.
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188 Responses to Mephedrone: The Facts

  1. Alex says:

    Do you sell this?

  2. Synchronium says:

    Heh, no.

    While I would say it’s reas­on­ably safe, I wouldn’t want to bet my entire live­li­hood on it!

    I’ll also say now — please no one post vendor links in the com­ments. I’ve removed similar from the JWH-​​018 posts and I’ll do the same here.

  3. PoisonedV says:

    Heh, heard about this on some alarmist face­book group. I won’t be trying it myself, doesn’t seem to be wide­spread at all in the us, plus it’s prob­ably covered as an analog. Not too fond of stim­u­lants or mdma, anyway. I hope the next new hot drug on the market is some­thing fun and psychedelic!

  4. laurence says:

    What an excel­lent, accurate, bal­anced article this is!

    Total truth from someone who knows the facts and the issues!

  5. Phil says:

    Really impressed with this, well done, anyone inter­ested in this should really check out Trans­form. They’re the people lob­bying the gov­er­ment (UK & EU) on your behalf to try and stop pro­hib­i­tion, simply put when this becomes illeagal (and it’s looking like it will after xmas) the quality of the product will go down and the risks will go up. If you want to know more put “trans­form drug” into your search engine. Nothing is going to change unless we have a voice, and the bigger the voice the more notice the author­ites will have to take.

  6. Jared says:

    Hope­fully it’s a good sub­sti­tute during the MDMA drought here in Aus­tralia… I’m getting in on it before it’s illegal :)

  7. Synchronium says:

    PoisonedV: Here’s a thread about mephed­rone in the us: http://​www​.drugs​-forum​.com/​f​o​r​u​m​/​s​h​o​w​t​h​r​e​a​d​.​p​h​p​?​t​=​1​0​9​418
    Also, there’re tonnes of psy­che­delic research chems out there. Check out 4-​​AcO-​​DMT — all the fun of mush­rooms in powder form.

    Laurence: Thanks!

    Phil: Thanks too! I was made aware of Trans­form after they linked to my pre­vious Nutt Sacked art­icles from their blog. Good to know someone out there’s doing some­thing. I think the best way to keep everyone safe would be if the gov­ern­ment charged £20 tax on the gram. They’d make a fortune and the addic­tion poten­tial would be decreased quite a bit.

    Jared: Be careful though, AU police have made at least one seizure of some meph pills so far. I don’t think any charges have been pressed, but they’re getting pretty pissed off about it. Actu­ally, I think police in the UK have been doing the same thing — seizing it until they can analyse it.

  8. SmokeGuru says:

    I liked all the info on the write up and the way it was written..

    But theres no key info on dosage or any­thing on what one should really be taking..? Unless I com­pletely missed it (Don’t gun me down if I have).

  9. abitkinky says:

    Fant­astic artical,
    thank you for taking the time to write such an inform­ative artical on the subject. I heard about this drug at the weekend (slow on the uptake some­times) so wanted to stat­isfy my curi­osity on this and find out the up’s and down’s of this mephed­rone. I feel fairly well informed from reading this artical and make a fair judge­ment on my actions going forward

  10. Synchronium says:

    Smoke­Guru: There was some inform­a­tion up there, but I’ve now put it under its own heading for clarity.

    I’ve also updated the side effects section to include some inform­a­tion on autoim­mune vas­cu­litis. It could be wrong, but I’d rather be safe than not.

    abitkinky: Thanks a lot. Be safe!

  11. Adam says:

    YOU WANT TO KNOW THIS
    =====================
    People, I have not read your 10 com­ments [YET] as these are finals but I can always find time to share this vital information.

    Drugs that begin with meth– or methyl– have the ability to cross your blood brain barrier. This means they affect every single part of your brain (read: your per­son­ality, psyche, con­scious­ness) at once. This means you have no way of tracking the effects as they take hold, you are going to become a dif­ferent person.

    I took Ritalin for 5 years as a VERY young child, which is METHyl­pheidate. Coke heads inject it too, for a cheap, legal, readily avail­able crack-​​like high. After I quit cold turkey at around 14 I changed forever. Every day life was like being a crack head without a rock; lit­er­ally. I had never used any other drug but that was the exact chem­ical situ­ation my brain was in. When you change every part of your brain at once you can’t control or under­stand any of it, you are 100% chan­ging WHO you are.

    Even more inter­esting…
    I was almost 18 13rd before I real­ized what was going on with my emo­tions. That is exactly twice the age I was when I began using Ritalin 2 mos. after my 9th Birthday. I learned so much so fast about the world and myself that week that it wasn’t long before I noticed the age thing; that period of my life was on my mind a lot as that 18 y.o. week drew near but didn’t know why until I was exactly twice as old.
    I have con­cluded that treating our bodies like machines turns our minds into them, and at that point YOU ARE TRULY LOST.

    I hope you read this, I am a total lunatic because of the early child­hood speed abuse forced on me. You would never let me talk to you for this long in person and I wouldn’t want to. You have all been warned, ask a real junkie if you don’t believe me. To this day my only solace is marijuana and without it I slowly go back to the old ways imprinted on my cortex.

    Nothing with meth– or methyl-​​, that is all.

  12. Adam says:

    Sorry if that was touchy/​too per­sonal but I want people to under­stand these feel­ings so as to FEAR them, not pity them
    believe me I have no use for that

  13. Emma says:

    I read your article with great interest, lots of information.

    I wondered if it woul dbe pos­sible for you to site where some of the inform­a­tion came from??

    I am par­tic­u­larly inter­ested in

    evid­ence coming forward for autoim­mune vasculitis

    Tol­er­ance can also develop, so more is required for the same effect.

  14. Me says:

    To Adam:
    For a drug to effect the brain it has to be able to cross the blood brain barrier (BBB), thats how drugs get into the brain from the blood, if they couldn’t they couldn’t have a direct on the brain.
    As with all other drugs which cross the BBB, they cross non-​​selectively, as in their entry is dependent on concentration-​​gradient of a par­tic­ular chem­ical, there aren’t areas of the brain where the BBB is more of a barrier than else­where. This means that a drug (for drugs effecting “classical“synaptic trans­mis­sion) exhibits (gen­er­ally) greater efficacy in areas where spe­cific receptors are present or present in greater numbers.

  15. Overfiend says:

    Rocking stuff. Have used reg­u­lary last few weeks and have taken in various ways.…Snort, IV, Oral. I com­pletely under­stand the pos­sib­ility of harm from it but for now its cheap, won’t get me arested and has less imme­diate unwanted side effects than E, Speed, Coke, Ket­amine or any other drug i’ve taken.
    I think on anna­lysis of anyone that has come to harm while taking it that we will prob­ably find they have been mixing it up with other drugs such as Ketamine.

    Tol­er­ance does develop of course. FFS take any drug often enough and tol­er­ance will develop. Hell I took a IV hit of half a gram just last night and then the couple of grams I took spread out through the night.…why because i’ve been taking it all week and i’ve begun to build a tol­er­ance.
    Lets get in per­spective though. Its not Heroin and tol­er­ance to a drug is revers­able, just stop taking the crap. Me I aint taking anymore now till next week prob­ably and when I do I’ll bloody well enjoy it in the know­ledge that I’ll not fight with anyone, drink drive or over­dose myself to an early grave.

    One thing i will say is if anyone is gonna IV it then at least have the bloody sense to not share neddles or any other equip­ment that may come in contact with blood/​needles etc.…I.E Water vials or anything.

    Peace Out

  16. Synchronium says:

    Adam: I don’t think the methyl group has much to do with it. Take loper­amide (4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]- N,N–dimethyl–2,2-diphenylbutanamide) for example, prized for not being able to cross the blood-​​brain barrier.

    Emma: The autoim­mune stuff is just a theory at the moment — no evid­ence one way or the other. This thread makes for some inter­esting reading though: http://​www​.drugs​-forum​.com/​f​o​r​u​m​/​s​h​o​w​t​h​r​e​a​d​.​p​h​p​?​t​=​8​9​052

    Over­fiend: IVing half a gram is insane, espe­cially with such a new drug with such a dan­gerous tox profile. Good call on taking a break for a bit, although you might want to leave it a couple of months or so for that tol­er­ance to subside. What’s your weekly use like? Is it all IVed? If so, how’re your veins doing?

  17. Overfiend says:

    Yeah I agree com­pletely that IV’n half a gram is mental. Won’t repeat in a hurry for that reason alone. My cur­rently usuage varies. Any­where from 2 grams to 8 in a week usually all on one night. IV’n it the last 2 weeks and my veins are fine. So long as i don’t miss then no real issues. A little bit os hard­ning but thats it. They haven’t colasped and I haven’t be using Citrix, just plain sterile water.

  18. Synchronium says:

    Thanks for that. Please keep us all updated as the weeks go by!

  19. Overfiend says:

    Will do. The brother is gonna do the same half gram tomorrow in one go.(he did it first and got me too the last time) He figures do it first instead of after taking hits most of night and then doing. Wants to see what sort of hit he’ll get when its first hit of day. I’ll let you know how that goes. He’ll no doubt be wanting me to also. If i don’t report back then we’ve died and it can be a lesson to others. Madness maybe, insane probaly, fun most def­in­itely :P

    Oh it may also be worth noting that on the 1st weekend bender of_​MMC i did develop a nasty tongue ulcer. I’ve never had one in my life. I have however put this down to several days of binging on the stuff and having not slept during this time. Body run down etc etc. May be worth noting tho.

  20. concerned mother says:

    some of the com­ments really concern me — it appears that they promote the taking of this drug which to young people is like giving them the excuse to try it. I am aware that kids as young as 13 are trying this as ITS NOT ILLEGAL and there­fore must be alright. My daugh­ters friend has been taking it over the last couple of months and it doesn’t seem to matter what my daughter says to her (they are only 15) she thinks its great. We live in a small place where two boys have already been taken to hos­pital after taking “bubbles”. They were drinking as well but then again they are too young to under­stand any of the con­sequences of taking drugs — espe­cially legal ones. I hope that when you all have chil­dren you will be as keen to indulge in drug taking and openly see it as accept­able when your kids can access these sites as well.

  21. Synchronium says:

    Con­cerned Mother: I can see where you’re coming from, but I disagree.

    Firstly, chil­dren can access ANY website an adult can, the only real barrier to entry being some kind of payment (whether buying a product or mem­ber­ship), so chil­dren will always be able to find free info on any topic they want. Would you not agree that some­where like this with a massive harm reduc­tion article before the com­ments is much better to read than just a forum full of exper­i­ence reports? At least if a child ends up here, he’ll have to read the article above in its entirety (warn­ings, mis­con­cep­tions, safe usage tips ‘n’ all) before he gets to the com­ments. The amount I write about phar­ma­co­logy and legis­la­tion is enough to keep most kids away anyway.

    Also, I’ve never men­tioned any­where that I take drugs (apart from a post about blue lotus and guarana from over a year ago). When I have kids, I will inform them of the dangers of drugs, including alcohol and tobacco. They’ll get a stern talking to and a very boring phar­ma­co­logy lesson if they ever take any­thing before they’re adults, but I won’t stop them from learning about them or feed them false inform­a­tion to scare them away.

    The only solu­tion that would make you happy is to censor the entire internet according to your par­enting style. Thank­fully, this can be achieved with soft­ware on your com­puter, rather than con­tacting every site out there with your prob­lems. Not that I agree with this approach, but as a con­cerned parent, I’d be mon­it­oring my kids’ internet access.

    You’re in a great pos­i­tion here — you know your daughter is inter­ested in mephed­rone to some extent and that she’s familiar with it. Instead of trying to stop her getting inform­a­tion on it, you should talk to her about it and perhaps get her to read this article. Right now, it seems she thinks that there’s a cool, new, fun stim­u­lant out there and you’re just saying “it’s bad, don’t do it” with no more reas­oning than that. Tell her why she shouldn’t take it, explain that no one knows the phar­ma­co­logy behind it, explain that there are neg­ative side effects, tell her about how drugs can affect a devel­oping brain dif­fer­ently than an adult’s.

  22. knows well says:

    THIS DRUG IS EXTREAMLY ADDICTIVE, MOST OF MY FRIENDS HAVE NOW BECOME ADDICTIVE BECAUSE OF STUPID COM­MENTS LIK THISITS LEGAL ITS GRAND”! ITS WORSE THEN PILLS OR COKE.….ALOT WORSE!!!

  23. Overfiend says:

    They are only addictied cause they are twats. Christ my usuage is more than most and i aint taken it now in over a week. Am i getting with­drawl? Nooo. Wind your neck in. If they can’t handdle it then they obi­vi­ously have addictive tend­en­cies. They should prob­ably stay away from any­thing addictive including chocolate.

  24. Laurence says:

    A few points to welcome in the New Year from someone who has used a range of recre­ational drugs, fairly sens­ibly, throughout his very long life.…

    1. I can confirm that mephed­rone is amaz­ingly addictive because of its ready avail­ab­ility, purity of pro­duc­tion, purity of buzz, short euphoric life, cost to buy and (apart from nose mucus floods) lack of apparent short term after effects.

    2. It WILL be clas­si­fied in a few months and prob­ably as Class A as it is so similar to coke and ecstacy. There­fore, easy access and low cost will drop out of the equa­tion. It will prob­ably still be avail­able on the street or via over­seas websites.

    3. Simply making this drug illegal will not impact on the per­sonal, psy­cho­lo­gical need for addictive per­son­al­ities to use these drugs, the lack of family dis­cip­lines or wider social issues which also contribute.

    4. The truth is that most people simply want to have fun and find legal altern­at­ives (such as alcohol) expensive and not to their liking.

    Have a happy and safe New Year

  25. Synchronium says:

    Over­fiend: Thanks for reporting back. Glad to know you’re coping without it! Any lasting symptoms?

    Laurence: That’s almost exactly how I feel. I actu­ally gave an inter­view about mephed­rone to Drug­Scope the other day for pub­lic­a­tion in their monthly this Jan. Since my opinion will form a minus­cule part of the article, I was thinking of writing a post soon about the pros, cons & altern­at­ives of clas­si­fying mephed­rone. Thanks for letting me know that’s some­thing at least one member of this com­munity will enjoy. :)

  26. anxious parent says:

    My son and his friends have been using mephed­rone for over a month and it has turned them all into lying, cold, cal­cu­lating, manip­u­lative, scheming and seem­ingly conscience-​​free sociopaths.

    My interest in this site is to enquire whether there is a drug test kit which will reli­ably reveal the use of this sub­stance. I want to do a ‘You have 14 days to clean up your act before I start testing, and if you won’t agree, all the things that you rely on for the other highs in your life, like your school, your phone and your laptop will be taken away, because we love you’ type approach.

    Whilst I would support the capa­cit­ated decision-​​making of any over 18 year old to screw with their bodies or their minds in the privacy of their own home, no-​​one is going to per­suade me that taking this ghastly sub­stance is a legit­imate choice for a teen. I am seeing first hand the psy­cho­lo­gic­ally addictive qual­ities, never mind the phar­ma­co­lo­gical ones. I want to like my child, but he is making it really really hard, and I want to help him sooner rather than later.

    Thanks for the inform­a­tion by the way — best site I have found on the subject.

  27. adam says:

    re: anxious parent

    I was recently living in my parent’s house, going to high school and began exper­i­menting with drugs so maybe I can help you before you test your son. But first in case I forget, you should visit erowid​.org once in a while when you want to know about some­thing your son is or may be taking. Here’s their page on this drug: http://​www​.erowid​.org/​c​h​e​m​i​c​a​l​s​/​4​_​m​e​t​h​y​l​m​e​t​h​c​a​t​h​i​n​o​n​e​/​4​_​m​e​t​h​y​l​m​e​t​h​c​a​t​h​i​n​o​n​e​.​s​h​tml

    Everyone can trust erowid, nobody has ever actu­ally visited without being impressed. It’s a DARE cop’s worst night­mare: free, unbiased data for almost any drug on earth!

    Anyway now that you know about erowid, I just wanted to say that any changes or feel­ings you’ve noticed in him since he began using are 99% likely to be related to feel­ings or changes in him that led to his choice to use a drug, other than that I would just tell him to smoke pot instead. It’s been clear in recent years that the gateway theory is the opposite of the truth, a lot of hard– and syn­thetic– drug users with addic­tions can use weed to wean off of almost any­thing. I hope that’s not out­rageous for you, but if he’s willing to abuse syn­thetics than he has prob­ably smoked pot before (not that I believe in the “gateway” theory but that is still more likely).

    If he has smoked pot try asking him why it was not enough or if he was just curious, he is prob­ably for­get­ting how he enjoyed things without it as the depend­ency envelops. Maybe try smoking it with him and observe the change in his beha­viour, you’ll under­stand it better, like Jane Goodall with the chimps. :-)

  28. anxious parent says:

    Adam, thanks very much. Am not shocked at the idea of smoking pot instead of doing this, but think he has done it the other way around already.

    He has always been intel­li­gent, lazy, un-​​boundaried, and inter­ested in thrill-​​seeking, but is cunning with it, and lacking in emphathy, which is why we are taking this so seriously.

    I looked at Erowid and agree it is a bril­liant site. But unfor­tu­nately, no use on my ques­tion about drug testing for this par­tic­ular drug.

    Does no-​​one involved in drugs culture even know whether a drug test is being developed, since this drug is one of those that is being clas­si­fied, so far as I can tell, in the spring?

    [Erowid — Reports with at least 4-​​Methylmethcathinone or meth­cath­inone in com­bin­a­tion with Drug Testing — zero]

  29. Synchronium says:

    Anxious Parent: It’s unlikely that a test has been developed, or is being developed at the moment since it’s legal. There are a number of more eso­teric illegal drugs that standard tests won’t pick up, so it’s unlikely that any­thing exists for mephedrone.

    When it’s even­tu­ally sched­uled, it will be much harder to get hold of, so the users will be forced back onto similar illegal drugs, most of which are tested for, so it’s unlikely a simple test for mephed­rone will ever become available.

    This article may be of interest: Drug Testing — All You Need To Know.

  30. anxious parent says:

    Thanks again — as I feared. We’re off to speak to some indus­trial chem­ists — how hard can it be, if one under­stands assaying and chro­mo­tram science? It’s extraordinary no-​​one sees the Parents Of Under 18s market for this as a busi­ness oppor­tunity, I have to say! I guess everyone’s too busy enjoying their euphoria.…

  31. Synchronium says:

    Anxious Parent: It’s totally pos­sible in a lab, but I thought you were looking for a cheap ELISA-​​based drug test. Cro­ma­to­graphy can cer­tainly tell you what’s in a sample, but it’s a very expensive, labor­ious process — cer­tainly not suit­able for regular use unless you own your own equipment.

    Not sure if any mephed­rone makes it to the urine though. If it doesn’t, then the chemist would have to look for its meta­bol­ites, which a) may or may not be present in urine and b) are cur­rently unknown, since no research has been done on it.

  32. anxious parent says:

    Thanks for the cla­ri­fic­a­tion and for raising the meta­bolite issue. I was looking for a quickie test, as a screen, for home use, but I think that inde­pendent school heads will pay for the devel­op­ment of a lab test, rather than lose half their pupils.… or be seen to be putting their heads in the sand.

  33. Synchronium says:

    Some great and far less intrusive “home tests” would be looking for changes in beha­viour, mood and appetite or phys­ical symp­toms such as dis­col­our­a­tion of the hands (or feet, knees and elbows, but hands are prob­ably most visible), dark rings under the eyes, how often they blow their nose, con­stantly chapped lips.

    Obvi­ously these aren’t def­inite signs of mephed­rone use on their own, but if you know your kid may be using it or has used it in the past, they may be an indication.

    Have you tried talking to any of these kids about it? If so, what issues have been the main talking points?

  34. anxious parent says:

    All those signs are there. Along with eczema and light nosebleeds. But I don’t know if this is his­toric, from a few days or at least a week ago, or current.

    We have talked about it but I have been told a given thing — ie we have stopped — appar­ently with open­ness and con­tri­tion — and then had the opposite told to me — ie they are still all doing it — by other people who care for them. So I don’t think I am getting the truth from them, which adds to the problem of trust.

    The main point has been that they do it because they CAN, because it’s cheap, because it makes them feel they are in a gang with some­thing in common, because they feel grown up, and cool, they all have some­thing to be secretive about, which gives them some meaning, etc. All these kids are affluent and rel­at­ively well put together kids, and they all know the facts.

  35. knows well says:

    This is crazy soon you are all going to realise the effects of this drug…it has exploded all over my town everyone does it and have become sooooo paranoid.…This drug is evil…my own sister is a para­noid mess.…its des­troyed my family.…stay away from it!!!!!!!!

  36. Overfiend says:

    @ Knows Well, I can com­pletely under­stand your adversity to 4-​​MMC. However to say the Drug is evil is a little melo­dra­matic surely. I don’t mean to belittle your opinion at all.
    I appre­ciate that you may have had a bad exper­i­ence and/​or con­tinue to do so as a result of 4-​​MMC being taken by a family member.
    I will however say that in my own exper­i­ence which is fairly vast in all drugs that to blame 4-​​MMC on peoples para­noia could be a little restrictive. Prehaps i’m wrong but I’ve yet to exper­i­ence any such symp­toms or to witness any such beha­vi­oural traits in my friends or anyone I know to take it. I would suggest that prehaps in your case the indi­viduals con­cerned are also users of Can­nabis and/​or prehaps other drugs also.
    Maybe thats all a stab in the dark and prehaps i’m com­pletely wrong in my thoughts. Apo­lo­gies if this is the case. However i’m 31 yrs of age and have been a fairly regular user of one drug or another since the age of 18 so have a fair bit of exper­i­ence on the pro’s and con’s.

    Just my opinion and by no means a defin­itive view. I hope your family life improves.

    Peace Out.

  37. Synchronium says:

    Anxious Parent: I’m not a health care pro­fes­sional, so never rely solely on my advice. That said, perhaps you could try showing these kids what they’re doing to them­selves — not in the form of a telling off, but just listing a few things. Point out to them that all of these signs of their drug use are visible to everyone else. You could even take a few pic­tures of your own kid’s hands, etc, just to show them how unusual that kind of dis­col­our­a­tion is. Perhaps also explain how their beha­viour has affected other people (you, the other kids’ families):

    My son and his friends have been using mephed­rone for over a month and it has turned them all into lying, cold, cal­cu­lating, manip­u­lative, scheming and seem­ingly conscience-​​free sociopaths.

    Let them know (not in an angry way) that because of their drug use, you can no longer trust them. Is all that really worth it to feel cool?

    Knows well: That was a pretty poor comment. What makes you think I haven’t “real­ised the effects of this drug”? I’d imagine I know more about it that most people, including your­self, con­sid­ering I wrote the above article.

    It seems that you have let per­sonal issues cloud your objectivity. Imagine those people who’s chil­dren die from taking ecstasy each year — the number of people is tiny, making ecstasy one of the safest drugs there is. For those parents, ecstasy is evil, but for the vast majority of people, it’s far from it. Do you or your family use any other drugs, including alcohol and tobacco? For some fam­ilies, those are the drugs that have caused the most hurt, despite the fact that many people don’t have any prob­lems with them.

    Your sister has made some poor choices, that’s it. When your sister takes mephed­rone, there are two entities there — your sister and the drug itself. Only one of those entities has a con­science, will, inten­tions, etc, and that’s your sister. Now *I* don’t think your sister is evil, but you’ve attached that label to the one thing in this scen­ario who has no effect on any­thing if left alone in a pile some­where, but only affects people who decide to put it in their bodies. Mephed­rone didn’t ask to be taken; it wasn’t fruit from the Tree O’ Know­ledge and your sister isn’t Eve, tempted by some external force (not that any of those things actu­ally happened…)

    Perhaps you should be less quick to blame a sub­stance for all your prob­lems and try talking to your sister. Explain to her the damage she’s done to your family and how her decisions have neg­at­ively affected everyone around her and not just herself. Perhaps there’s a reason she felt the need to take drugs. Do you know why that is, or have you just decided to blame the drug for all these issues?

  38. knows well says:

    im just after real­ising your pro­fes­sion Syn­chronium and i now realise why you have such a fucked up veiw on drugs.…you sell them (the so called “legal” ones)!! duuuhhh.…my apo­lo­gies i was under the impres­sion that this site was about the dangers of drugs…not pro­moting them…my bad…!!

    PEACE OUT

  39. Synchronium says:

    Knows well: If I worked in a bar, would you think the same thing?

    How is the above post pro­moting mephed­rone (which I don’t sell, see comment #2)?

    Also, this site was never about the “dangers of drugs”. It’s about all aspects of drugs. The dangers have cer­tainly been men­tioned, but the point was harm reduc­tion, which isn’t all about scaring people away with lies, false inform­a­tion and anec­dotes from morons. It’s about accepting that people will use a drug and trying to reduce the harm they cause to them­selves and others. What you suggest is the equi­valent of abstinence-​​only sex edu­ca­tion (which, as everyone knows, doesn’t work). Teaching people how to be as safe as pos­sible is the only way to keep people safe.

    I genu­inely worry for your sister. If this is the atti­tude and support she’s getting from you, she’s in much more danger than we pre­vi­ously thought. Going back to our sex edu­ca­tion analogy, your sister would be the one to end up preg­nant or with an infec­tion because she’s never heard of a condom. That kind of approach does NOT work.

    As a final point, please see this post.

  40. Slicedmind says:

    Knows well: a simple browse through Synchronium’s will reveal that he does not sell mephed­rone, there­fore we can assume that his posting about it on his blog is not to do with any vested interest in selling the product and that he might actu­ally have some useful advise as someone who has know­ledge and exper­i­ence within the industry. Hey, some of his advice doesn’t even sound half bad: listing side effects, tips on safe usage, some begin­ners inform­a­tion on where this craze has come from; hell, it almost sounds as if he is trying to help!

    I assume the title “knows well” was intended to be ironic? All you have con­trib­uted to this dis­cus­sion is a hys­ter­ical dis­trac­tion from a serious and con­structive debate and exchange of inform­a­tion. Your claims about its addict­ive­ness or com­par­isons of harm poten­tional com­pared to that of “pills and coke” typify the knee-​​jerk reac­tion which stig­mat­ises these drugs and mys­ti­fies them further, pre­venting the rational research into the phar­ma­co­logy and tox­icity of the drug at hand and the sub­sequent guid­ance and legis­la­tion that could be put in place to protect those vul­ner­able and those prone to over-​​indulgence.

  41. adam smith r says:

    I think its wicked better than any illigal drugs.You like music better it builds your con­fed­ence up.yeah it may be harmfal and addictive if your taking loads of it. i snort it but a have it 1 night a weak i dont get with­drawal and plus iam not that weak to get addicted.

  42. Slicedmind says:

    adam smith r: unfor­tu­nately, just by having a ‘normal’ brain you have the capa­city to become addicted to physiolo­gic­ally addictive sub­stances (whether or not mephed­rone is addictive has not been proven yet, though there are many accounts all over the web of it being so). However, sens­ible beha­viour and mod­er­a­tion (as it sounds like you have been prac­ti­cing) can prevent tolerance/​addictions devel­oping so I would say keep safe, and try not to be too harsh on those with addic­tion problems!

  43. Overfiend says:

    Well i’m under no illu­sions regarding it. I could quite happly take truck loads of the stuff. Myself and m8s all agree that out of all drugs we’ve tried since we were 18 (31 Now) that 4-​​MMC is the best ever.
    I have no doubt that it can and does give user a want for more but having used quite heavily for about 2 months + or -, that i do not feel addicted.
    Sure I could take for days on end and def­in­itely like to get some, but when I do without I DO NOT suffer from any with­drawl symp­tons so to speak and my friends and family agree that my per­son­ality hasn’t changed.

    Its clean in buzz and come down, cheap and side effects (imme­diate @least) are minimal.
    I still fre­quently say to the m8’s that we truely DO NOT KNOW THE SIDE EFFECTS longterm or even in the short of a couple of years of fairly regular use and that we could be F**king ourselves up but it never stopped me taking E,Speed,LSD,ketamine,MDMA,Nubain,Cannabis etc etc etc and we know the down side of most of those.

    For now I will con­tinue to use purely because its cheap and it seems for the moment to be a fairly safe drug.
    As with any Drug, mod­er­a­tion would seem to be the key and over indul­gence can indeed only be a bad thing, but that applies to all things in life.
    I have a friend that lives 100 miles from me who has been admitted to a mental health hos­pital just today. He uses reg­u­larly. However he also uses a mul­ti­tude of other drugs both illegal, legal and Pharma, has a history of depres­sion and past suicide attempts so i’m not going to blame the 4-​​MMC for his latest issues. Its a com­bin­a­tion of his life exper­i­ence, depres­sion etc that his mental state is fragile and has driven him to excess in drugs and alcohol.
    I also have no doubt that all the drugs he has been taking (including 4-​​MMC) have most def­in­itely not helped him at all and that if he does not stop taking them he will prob­ably never get out of the hole he is in for any lasting period of time.

    K my lengthly rant over. I’m Love the stuff and will con­tinue to take.
    I think all things in mod­er­a­tion.
    And if you are men­tally unstable in any way then you should not take drugs full stop.

    Peace Out

  44. Decker says:

    Inter­esting thread.. Rite first, there are plenty of forums out their ded­ic­ated to parents and whining. I nearly avoided this site when I saw the posts from mums. However this thread has a couple of sens­ible inform­ants on it.. Over­fiend, I have IV’d 1 Gram in one go and it blows my mind. I agree with everything you say, and as a drug user its not often i meet people that actully talk sence. Im always saying “are people taking the same drug as me or what” But I think what your talking about is pure. Of course addictive per­son­al­itys will no doubt grow a fond­ness or slight obses­sion with this drug. I will say that when takin this drug it would be advised to take a decent amount in first hit 0.1gram– 0.2gram. If to little is taken we (my Friends) have noticed anxiety, agitation,and gen­er­ally feeling shit, Untill u take more of-​​course. Stay away if u have an addictive per­son­ality, get any fucked up symp­tons, or are a light-​​weight.. I take on average 15grams per week at present.. I haven’t had any side effects or come down..
    This is a drug i have enjoyed for about 8months now but I have had few breaks of about 2 weeks every now and again between times..I Have no problem with addic­tion, I just stop and start and feel fit and as healthy as before I dis­covered„ I do recom­mend and suggest though that rest and food con­sump­tion are main­tained.. I find that sleep and eating aren’t affected by 4mmc, although you may not feel like eatin and/​or sleeping both eating and sleeping are easily achieved. I would like your thoughts regarding this Over­fiend and any other per­tinent inform­a­tion.
    Im so pissed off with all the stigma attached to drugs that no one has exper­i­enced or exper­i­enced prop­erly. Sure too much of any­thing is bad so please let there be no ambi­guity in my meaning. I am not recom­mending or advising people to start taking drugs. I would infact advise the opposite and tell any person out there to stay away. However if someone plans to or is taking drugs then I will not judge them and feel that they could be taking worse than a sub­stance like 4MMC. Hell I know enough alco­holics to see how bad its screws people up. This (4MMC) in my opinion is the cleanest, safest drug ever created. I have taken all drugs availi­able out there apart from heroin. Im not stupid and know the dangers of that road, I choose not to go down it.. Mephed­rone is sold legally there­fore is reg­u­lated to a point and people know what they’re getting for most part at the moment„ I buy nowhere other than online.. Purity and quality changes when bought off the street. Dealers are usually scum and will cut your goods with whatever they get their hands on. I sin­cerely hope that we don’t see it getting made illegal but I fear thats a bit optim­istic.
    Anyhow enough from me. I’ll def be taking a look in here in the future.
    For now be good, play safe and stay alive.

  45. adam smith says:

    yeah try not to have to much i would not say its com­pletley safe.iam not addicted to it but i do have it ounce a week lime 2 g. keep the comment coming.

  46. smithy says:

    ‘Anxious parent’ it seems to me that you’re not very anxious at all! It’s too right that you should be angry at them although I would approach it dif­fer­ently. No son/​daughter likes to see their mother cry as they are an adult figure and however old the child is, they will feel a true sense of guilt. In no way am I implying that you should cry to get your point across, but it may help the situ­ation. Let all your emo­tions out and your son will realise the true impact of his actions. Tell him that you are worried about how the ‘Mephed­rone’ is obvi­ously extremely bad for you and that you couldn’t bear to see him hurt. A good cry and a hug will heal things up for sure!

  47. anxious parent says:

    First, I have to ask Decker — is YOUR mother ‘whining’? Or maybe she doesn’t know you on a day-​​to-​​day basis any longer? Do YOU have a teenager?

    Sure, you don’t like people who have not ‘exper­i­enced’ the drug attaching ‘stigma’ to people like you, but you need to con­sider two things, I would suggest: people who know and live with the mephed­rone user ARE exper­i­en­cing the drug — through what it does to the user. And secondly, if YOU haven’t exper­i­enced par­ent­hood — well, your views are never going to have an impact on grown-​​ups, are they? all our choices make us behave in certain ways, and our beha­viour affects others. If you had seen your own child using his friends to make money, and main­taining a front about giving up, but being so memory-​​impaired or dis­tracted as to leave his face­book logged in online, then I think you’d think dif­fer­ently, and not be so stuck on how much fun it’s been for you, so far. How would a drug user ever see the effect it has on their per­son­ality, if they only ever hang out with people who don’t know, or people who are doing it too, and all are becoming more self-​​obsessed, as each line is done?

    Smithy — thanks for the advice, but my child is not always moved by my tears or hugs. It may be because boys are just hard wired to enjoy risk-​​taking and it carries them away when they are young teens. But I think he’s that way because I am that way,too, and it’s essen­tially rational not to let others’ feel­ings over­whelm you — because it does give them power over you. That’s part of why I think the drug is so dam­aging for him and his future: it’s numbing his sense of fair­ness about family life, his instinct for self-​​preservation of his own well-​​being and repu­ta­tion, his capa­city for kind­ness, emphathy, com­pas­sion etc — and even the ability that a teen SHOULD be devel­oping, even to pretend these things, if he knows enoguh about what the REAL world requires of adults. It’s self-​​harm without the scalpels, to my mind.

    What he WILL be moved by, I hope, is fear of having to leave the school he goes to at present — all inde­pendent schools have an ABUSE of LEGAL DRUGS policy, not just usage of illegal ones; and you only get once chance to stop. There’s also fear of becoming a pariah amongst his girl­friend, non-​​using friends and parents, since their houses are where he spends his time and he’s not doing it with uni­versal know­ledge and approval. ALL mums and dads are ‘whiners’, as per Decker’s view, believe me, when their kids are 14 and snorting chem­ic­ally untested stuff up their bloody noses. I won’t hes­itate to make those things come true, if I think he is con­tinuing to take the drug, and it will be tough love.

  48. Laurence says:

    Good luck anxious parent! I too am the parent of an intel­li­gent, sens­itive, pre­co­cious 9 year old daughter. She lives with her mother not me and I think that my use of recre­ational drugs such as mephed­rone would be limited/​non-​​existent if she was with me more than 1 day per week as I would want to be a good role model.

    I often think about how I will behave if/​when she tries drugs and your com­ments are making me reflect.….. so thanks!

  49. anxious parent says:

    A quick update on testing for all you users out there, since you are keen on actual exper­i­ence: mephed­rone tested pos­itive for methamphet­amine on a saliva screening test, whilst a urine test showed neg­ative, no doubt because of the way it meta­bol­ises. The test was done some 20 hours after usage and the user had taken 0.5g.

    I hope this shows up on Google, so that all anxious parents can go get them­selves some relief.

  50. Anon says:

    I have been doing mephed­rone for over a year now. I’d say on average every 3 weeks I will take some. I would estimate I have taken over 50 grams in my time.

    The drug has seemed to affected me in a direct opposite way to your son ‘anxious parent’. I am 19 years old and from the age of 15 to 18 I was quite a heavy cocaine user. That drug made me aggressive and depressed which reflected in my awful atti­tude towards my parents. I had several argu­ments with them (before their dis­covery in my usage of the sub­stance) and I treated them in a dispic­able manner.

    After they ‘acci­dently’ dis­covered my life-​​destroying habbit I stopped for a while before I dis­covered mephed­rone. Whilst I thor­oughly enjoyed the use of MDMA the risks with buying it illegal (not as advert­ised, laced, impure etc.) were becoming too risky for me so I was pleased to be getting some­thing that I mostly knew what I was instore for. Now I have a much better rela­tion­ship with my parents, rather than coming home from a 3 day binge and spending the time in bed angry I am a much more lively and social person. The con­fid­ence I lacked in social situ­ations is des­troyed and the hor­rible feel­ings I got from alcohol ses­sions, some­thing I indulged in far too much, are gone. I feel awake and fine the next day. I am a lot more happy in myself and everyone I know would agree. My uni­ver­sity work has improved, my weight has gone to a safe amount rather than the mere 14 BMI level it was at just over 1 year ago.

    I believe the drug needs to be used in correct mod­er­a­tion, the same with everything and this site help­fully instructs people on the neg­at­ives and post­ives so people can right­fully decide for them­self what to do. It is a lot better than being cen­sored and being fed lies that upon dis­cov­ering the sub­stance will be demol­ished and then it will be dif­fi­cult to dis­tin­guish the truth. I was always told coke was hor­rible and one line could kill you but when I had some and had a won­derful euphoria I believed everything neg­ative I had been told was a lie. I just wish I had real­ised the true pos­itive points against the over­weighing neg­ative ones and made the clever choice myself.

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