Since my last post about the spice behind Spice (and other smoking mixtures such as Smoke, Serenity Now, K2, Sence, etc), it has been brought to my attention that some initial toxicology testing has been done on the synthetic cannabinoid JWH-018. Before we get down to the details however, here’s some pretty weird background information — the sponsor and provider of these studies wishes to remain anonymous! Unfortunately, this makes the whole thing a lot less credible, but since this is the only information we have right now, let’s hope someone else can verify these things at a later date. So far, one professor (who also wishes to remain anonymous) thinks these are real, but as of yet, no one is willing to put their name down on any kind of formal statement. If you, or anyone you know, has the relevant expertise to look over these studies, please drop me a line!
(Quick Update — A lot of people have been discussing and linking to this post, but there remains some suspicion that I have something to gain by saying the JWH-018 isn’t that harmful. Firstly, JWH-018 is now illegal in the UK. Secondly, as I mentioned just above this, if I have got anything wrong, please pick me up on it! If it turns out my analysis of the data is incorrect, I will correct it!)
Feel free to invent your own conspiracy theories, but for now, let’s take a look at the data. You can download the PDF documents in this Zip file [2.04 MB]
CYP450 Inhibition Assay
This first assay looks at the effect of a drug on specific enzymes in your liver. These Cytochrome P450 enzymes are responsible for metabolising the vast majority of drugs you might put in your body, so if you’ve got too much of one drug in your system (ie paracetamol/acetaminophen), then other drugs that are also metabolised by these enzymes (ie alcohol) may compete for these enzymes and so hang around in your system for longer. As you can imagine, it’s important to understand how one drug may affect the metabolism of another, in case of any disasterous drug-drug interactions.
Results: JWH-018 will probably interact with the metabolism of other drugs, so more in vivo work is necessary.
hERG Binding Assay
hERG stands for human Ether-à-go-go Related Gene. This gene codes for a particular type of potassium channel found on heart tissue. This channel pumps potassium ions out of the heart muscle cells and are critical in coördinating the heart’s electrical activity. Unfortunately, these channels are a prime target for drugs to bind to, disrupting their function. This can lead to “Long QT Syndrome”, associated with fainting and can lead to sudden death, so you can see why these kinds of tests are important. Here’s a typical ECG recording showing what’s called the “QT interval” shown in blue, which lasts for longer than it should do if these channels are disrupted.
Results: JWH-018 does not interfere with these channels. That’s a good thing.
Cytotoxicity Assay
This simple test essentially looks at how many cells die when you perfuse them with a drug. The more cells that die, the more toxic the drug.
Results: JWH-018 is not cytotoxic at low concentrations.
GreenScreen HC Genotoxicity Assay
This assay looks at how much a drug will interfere with our DNA. Typically, anything that damages DNA is bad news, being potentially carcinogenic, making the rationale behind this test glaringly obvious. This test was also performed in the presence of a fraction taken from liver cells, which will break down the drug. This not only checks if the drug will damage DNA, but also its breakdown products.
Results: JWH-018 does not damage DNA, so shouldn’t give you cancer.
Rat Repeat Toxicity Assay
Guess what happens in this experiment. A number of renagade lab rats looking for a bad time are rounded up and promised free drugs (kind of like Pleasure Island from Pinocchio; that shit was scary!). The rats are then dosed up and observed. Initially, they appear lethargic (read: totally baked) but a few of them died at higher doses. This appears to be down to problems breathing rather than organ toxicity, but only affected the male rats, who appeared more sensitive to the compound. The drug didn’t appear to accumulate in their systems either, but they did lose some weight, probably because they couldn’t be arsed to eat. JWH-018 showed a huge potency and was found to be tachyphylactic (my new favourite word — it means that more of a drug is required to reach the same state following an initial dosage).
Results: According to FDA guidelines, the human equivalent dose is 0.016 mg/kg but it should be tested in other species before this can be seen as reliable!
Rat Pharmacokinetics
Data is collected on a number of different “pharmacokinetic” aspects of the drug, such as how it is absorbed, distributed throughout the body, metabolised and excreted, which can help with the design of future clinical trials.
Results: JWH-018 is distributed well throughout the rat’s tissues. Metabolism and excretion are normal, with a plasma half-life of approximately 2 hours
Summary
Well, from the looks of these tests, JWH-018 seems to be pretty safe, but unless you want to piss off Ben Goldacre, it would be wise not to rely on this “test tube data” entirely. Also, like I said before, we don’t know where this data has come from, clouding the issue even further.
Feel free to ask any questions in the comments.
Big thanks to Alfa @ Drugs-Forum.com for letting me know about these studies. You can read all about JWH-018 on their Drugs Wiki.
COMMENTS IN THIS THREAD ARE NOW CLOSED. YOU CAN CONTINUE DISCUSSING SYNTHETIC CANNABINOIDS HERE OR INDIVIDUAL SMOKING MIXTURES HERE.
Would jwh-018 show up as THC in a urine,blood,hair folicule test? Since this is a relitively new compound. How much testing is actually being done on it? I wish somone with some credibility would be able to do some testing on this.
No, it won’t show up on a normal drug test.
The only similarities between this and THC are the receptors they both bind to.
After haviing found Bad Science, I think I should change my homepage! By luck I happened to find it by posting the link to this page on my website.
If I was on a desert island with just portal… give me more Bad Science!
But Science is good… and getting better. Just look what they can do with chemicals nowdays. Research continues.
Whether a drug is dangerous or not will not make any difference to the government in deciding whether to ban it. If it gets you high, in their minds, it is bad. If it is not dangerous, they will simply lie to people and tell them it is dangerous and ban it anyway.
The Gov’t wants to collect TAXES more, I think, than just about anything. They allow dangerous drugs and activities to remain legal in order to get tax revenue, despite the known risks.
People ALWAYS will want to gain cosmic insights, get loaded, zone out, get laid, and have adrenaline rushes… and will take whatever measures they feel necessary to get them.
If the Gov’t wants to declare JWH-018 as a danger to what — society? — then they can sure outlaw it, for what it’s worth to do so. The “War On Drugs” will continue — and to MY way of seeing things — THAT’S the REAL danger!!
regardless of its safety it may be it is not a patch on the real thing.Its like comparing rough cider to champagne.Personally i think the synthetic cannabis products are horrible and fail to see what the point is unlesss you are real desparate to get high.My advise if you can’t thec real thing do some cardia vascular excerise or yoga and do’nt waste your money on such awlful products
Chris (& possibly Tim): You might like to have a read of this post about religion’s role in keeping drugs illegal.
Motlly: Luckily, a lot of people disagree! In fact, some people prefer them to cannabis. I guess they’re also useful if all you can get hold of is shitty soapbar as sam commented on Can I Get High Legally?.
Thanks for the links, Synchronium.
For my opinion to count in the world, I have to make it known somehow. And my opinion is that whatever results in the least amount of harm, to the most people, is a GOOD THING.
Keeping natural substances illegal increases the incidence of violent crime, ruined relationships and lost opportunities pretty much any way you cut it — in MY book. Anyone who can defend a “War On Drugs” HAS to be messed up!
The beauty of a substance like jwh-018 is that its capable of giving people what they want, at a lower cost, in a pure form with a set dosage, and less apparent health risks, too.
It can be regulated by taxation, and since not everyone can or wants to produce it (as compared to throwing some weed seeds in the dirt) there’s less chance of a violent black market springing up if responsible parties are trusted to produce it under laboratory conditions.
If there’s no way to ELIMINATE risks of inevitable human activities and desires — why not take the next best step and minimize them as much as possible? As much as the conservatives and religious right would have otherwise… the simple truth is the genie is out of the bottle and ain’t about to climb back in.
I passed a hospital drug screen having smoked a jwh-018 fortified herbal blend daily for about a week before the test. JWH-018 will not cause you to fail a drug test.
im on probation and i think it would take them months to figure out the what they were looking for. my inpute on jwh-018 four stare high. synthetic supplys has a very good herbal mix called budda blend for a great price 5 grams for 30 dollars.stronger than pep spice spice gold ect.….…
they cant win the war on drugs anyway!
I have been smoking an herbal blend called Stryker for about a week now. I have noticed some lower back stiffness and aches-could this be related? I’m a little scared, as the package was totally shady, no ingredients listed, no manufacturer name-NOTHING!
I do have to say though, this herbal blend, much like Serenity Now Herbal incense, is totally intense and very long lasting! If anyone has had any similar side effects, please post!
personally i like it..medically its good to kno about some of this stuff .. and i always have some to share..
My sons friend just smoked some jwh-018 that he purchased on ebay and is now in the emergency room and can’t breath on his own„this stuff is really dangrous
Yes jwh is Toxic.…
Only after 5 year of abuse.
its come to the surface…
If you want to use 018.
then go ahead.
but let me tell you.. in the end, you will give it up
Spaced out: Perhaps you know something we don’t. Got any sauce for those facts?
My wise old daddy told me years and years ago that “Too much of ANYTHING is not good” — and I believe him.
What constitutes Jwh-018 “abuse”? Once a day? Or week? Wake and bake and stay loaded all day, day in and day out? Guess we all have to determine that for ourselves.
As with any other substance/drug, it can indeed be dangerous or even deadly, I suppose… even as if you were to consume too much WATER it could kill you, too. The problem with this chemical is that it is effective in such TEENSY TINY quantities that incautious people will inevitably sometimes take too much and get wigged out from it.
Know your tolerance and know your doseages, and take care!
its considerably nore potent that thc, if you like did a hot knife with it or something it would be like taking loads of hits of pure thc oil all at once, you have to dilute it or you will overdose and end up in a bad state, like if you smoke waaaaay too much weed i guess…
I wonder what the effects are when the substance is used in a vaporizer?
I’ve now had a number of experiencea with JWH-018. Personally, I love it. I’m on probation and this is the only way I was able to comfortably quit smoking weed. I find the buzz to be identical to marijuana at loto moderate doses but the main problem is dosing correctly. Without a milligram scale it can be very east to put out too much. A couple people around town and I have experienced a high dose and its not very pleasant. Whatever you do, be careful because it can cause panic attacks and difficulty breathing. We found that a mound about the size of a pot seed is a good dose to start with. Once you grow a little tolerance to it then you can dose a little higher. In the event that you do dose too high, don’t freak out and don’t fight it. It’s stronger than you. The best thing to do is just sit back and go along for the ride until you can grasp it. Best of luck and be careful.
Can I fail a drug court test by smoking Serenity Now Herbal Incense? Feels like I smoke that good and I do not want to piss for these people and have to do 30 days .….….like asap
ya watch e-bay, my pet monkey got JWH-018 200 mg’s and and when he ran out to the mailbox 2 days later it was there! but.. it was prolly only 30 – 50% pure, this is the dangerous part, not truly knowing how much to put in when the batch is “cut”, be careful, but i can also say since i was raided for 26 plants, (all attitude feminized seeds, 10 white dwarfs were ready for harvest, and the others were in 3 weeks bloom, white widow ss haze, etc…fox farm certified!) errrrrrrrrr anyway i have very little money and have found it nice to buy a couple gram of cannibus and a sizable amount of jwh-018, jwh-073 w/e theres now 2 more also. anyways its nice to mix a hit or two of real cannibus with 018 to get a lil more than a meranol effect (thc pill) very cerebral and nice by itself, but feels more comrortable with some real erb, this is a cheap way to stretch a budget if you have true nausea/pain issues like me. unfortunately im from the states and there is no herbal blends i know of here, im sure when or if im tried (idk wuts goin on at the moment as i do have serious medical ailments) i will find an herbal blend instead of just smokin some powder on a cigg, those herbal blends all range in types of jwh’s and have other weaker cannabanoid receptor attaching chems. in them, i here it is a good way to go if you know a good vendor for a spice that says whats in it. I don’t know any. my monkey wants to know though, he liked my plants to.
Serenity Now is Awesome, and I passed my drug test just fine! If you are scared just go to the drug store and get an at home test to ease your mind.
What is PARSLIJUANA?
Just a word I made up for 500 MG of JWH-018 mixed in with 5 grams of dried parsely flakes soaked until dry in a cup or so of 95% EverClear.
Almost makes one want to register the domain name, hmmm??
JWH-018 Is an excellent ‘drug’ — First few times of use will be like very similar to what most cannabis ‘users’ experienced. Very very stoned feeling, Maybe not fully enjoyable? But you learn to enjoy it more and I guess you nearly instantly build up a small tolerance to where you can enjoy it.
My experiences with this JWH-018 was nearly mirror’d as if i was taking weed for the first time.
As a 10 year cannabis smoker (daily) I enjoyed it, But After just one day of using jwh-018, rapidly built up a big tolerance to this, Exactly the same as weed/skunk what ever
But yeh, Nice to experience. Also nice to mix with weed or smoking blends.
I cant see any one going to hospital over this or anytihng. I smoked very high doses of it, Just ended up as if I smoked like half ounce of decent weed, monged out, needing food/water, Proper felt same for the following morning.
I rate it highly, Sad thing is the tolerance Issue.
I’m going to try out the other jwh-xxx’s — See what they’re saying!
Oh yeh nice site btw!
does anyone know if smoking blends like spice gold, smoke xxx that contain jwh everyday for a year cause some kind of cancer? and is jwh o18 safe to use or deadly? ive been hearing different things about this so i thought id ask.
Recently I ordered 5 grams of JWH-018 from [THE INTERNET]. The product came in 3 days and was of the highest quality and a good price. I gave a few of my friends some doses and told them how to safely dose yourself. Unfortunately, they gave some to friends too and didn’t explain the dosages and someone ended up going to the hospital because they thought they were going to die. Since they got it from someone who got it from someone, they didn’t know the proper name for it and the hospital thought they were given ghb. The girl was fine after about an hour but a lot of questions are now being asked. This stuff is awesome, but it’s no joke.
You can find JWH-018 of equal quality for considerably less if you look around… or even free (10MG) samples of it at [ANOTHER WEBSITE ON THE INTERNET]. I’ll be the first to agree, though, that this “awesome stuff” is definately “no joke”.
With that in mind, my advice is to make the straight chemical into a standardized, easy to use form that you can share with others that won’t get them in the emergency room to do ignorance of how to use it. The original “parslijuana” I made was toooo strong, so it was diluted to about 7 grams of parsley to 500 MG of JWH-018, soaked in a cup of 95% Everclear grain alcohol until dry.
This way, if shared with others, the instructions are “Take ONE hit every 1 – 2 hours as desired”. Those with a pre-existing tolerance buildup could manage two hits back to back… but most people (IMHO) will realize within 2 – 3 minutes that a single hit is all that is needed… or desired.
Hey all.….
UK readers might be interested in the following report to the Home Secretary from the Advisory Council on the Misuse of Drugs:
http://drugs.homeoffice.gov.uk/publication–
search/acmd/acmd-report-agonists?view=Binary
In addition, there’s an interesting link on the following page from the European Monitoring Center for Drugs and Drug Addiction regarding their recomendations for the control of Spice and synthetic cannabinoid agonists such as the JWH group:
http://www.emcdda.europa.eu/attachements.cfm/att_80086_EN_EMCDDA_Understanding%20the%20‘Spice’%20phenomenon_4Update%2020090813.pdf
The following was of special interest:
“The Commission-funded Psychonaut web mapping project continuously monitors the web for novel
compounds, using 9 languages, with the support of different tools/software (e.g. Google Insight, Blue Crab,
Boolean Search, InSite, Advanced Web Ranking and SerpSpy). The project monitors regularly more than
200 websites, forums and blogs which provide information on many compounds”
Hope I’ve not bored you all too silly.…
in a hospital blood scan. will serenity now contents show up ? and what will it show up as? i understand it wont show up in a piss test becuase the piss test would have to know what its looking for. but what about a full blown hospital blood scan that they give for a “on the job accident” , etc.
HairyCelt, that is very interesting stuff! I skimmed through it, and found it to be very interesting but really technical. Right now I am resorting to using ginko biloba mixed with piracetam to get my cerebral fix. This combination creates clear mindedness and alertness. I wish there was a legal substance that I could vaporize with no trouble.
I have over the used used forums like this in my exploration of drugs. So now I will give back. I have been doing JWH-018 for about 7 months now. The only thing that would give me a clue that I wasnt smoking weed is the way JWH is smoked. Other than that, to me, its like dank nugs. I am 34 and smoked since 14.…steadily. I was your typical pot head. Then as a result of a divorce and a narc wife, I had to quit pot…for my kids sake…I have custody. Well, I have had 2 piss test at work. Taken at a hospital, passed, no questions, 1 piss test for court, Redimed…Passed.…I was injured at work=workers comp.…Passed. It is safe to say you can pass test with no worries. I have went through about 8 grams now…I love it.As with any drug…responsible use, caution and respect will prove useful and ensure the fact that you can now be high all you want…and they cant even prove it. In closeing, I use a very small wire with a flat end…very very small…I find with no scales…this wire will only alow me to pick up a minimal amount at a time…but Ill just shut up now.….DAMN I LOVE JWH>HE should have gotten the nobel peace prize.…
Rather interesting to read how many people post about the JWH-018 and use terms as “I love this stuff”, “my beloved JWH” and such.
Seems like more people have found it to be of benefit than have gotten freaked out about it. Most everyone also mentions using it RESPONSIBLY — which should be a no-brainer with ANY substance/drug — but still, is good advice for Newbies.
Some will love it, for sure, and those who hate it just don’t like drugs or something, I guess. The drugs/drugs effects aren’t “the problem” with most drugs as much as the person who abuses them, eh?
Seems unlikely that NarcoTerrorists are gonna be gunning people down in Detroit to sell this stuff, so no problem there, either. Shucks, I wouldn’t even mind paying State sales tax on it if they/The Govt allowed it to be sold at the corner 7 – 11 at a resonable price.
Why not?
Hey everyone, my second post. I am reading the actual patent for this stuff and I am reading some interesting elements as such:
quote “DESCRIPTION OF SOME PREFERRED EMBODIMENTS
As used herein, a “therapeutically effective amount” of a compound, is the quantity of a compound which, when administered to an individual or animal, results in a sufficiently high level of that compound in the individual or animal to cause a discernible increase or decrease in stimulation of cannabinoid receptors. Physiological effects that result from cannabinoid receptor stimulation include analgesia, decreased nausea resulting from chemotherapy, sedation and increased appetite. Other physiological functions include relieving intraocular pressure in glaucoma patients and suppression of the immune system. Typically, about 10 mg/day to about 1,000 mg/day is a possible “therapeutically effective amount” for the inventive compounds. ”
10 mg per day… how much are you guys using?
The compound of the present invention can be administered by a variety of known methods, including orally, rectally, or by parenteral routes (e.g., intramuscular, intravenous, subcutaneous, nasal or topical). The form in which the compounds are administered will be determined by the route of administration. Such forms include, but are not limited to, capsular and tablet formulations (for oral and rectal administration), liquid formulations (for oral, intravenous, intramuscular or subcutaneous administration) and slow releasing microcarriers (for rectal, intramuscular or intravenous administration). The formulations can also contain a physiologically acceptable vehicle and optional adjuvants, flavorings, colorants and preservatives. Suitable physiologically to acceptable vehicles may include, for example, saline, sterile water, Ringer’s solution, and isotonic sodium chloride solutions. The specific dosage level of active ingredient will depend upon a number of factors, including, for example, biological activity of the particular preparation, age, body weight, sex and general health of the individual being treated.
So obviously, according to the patent, we don’t have to risk getting cancer by smoking it, we can actually use it topically on the skin and get an effect, or mix it in a liquid and drink it? Smoking is probably the worst way of using this stuff.
Here are my main concerns before attempting to try this stuff.
1) How can a person verify that the stuff they purchase is really pure? Which vendors are the best?
2) How can a person actually measure out 10, 20 or 30 mgs of the stuff?
3) Has anyone used this stuff in a method other then smoking it? I would be interested in vaporizing.
keep these posts rolling, knowledge is power,
btw, if you want the patent link here it is:
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=7241799.PN.&OS=PN/7241799&RS=PN/7241799
I know a fellow who uses JWH-018 orally and reports real good results from it. Dose size is unknown exactly, but estimated 5 – 10 MG. He says he’s never had a “bit too much” using it that way as compared to smoking it — where even a little “too much” can bring on undesireable side effects.
My wife has tried it orally both in about 3 – 6 MG amounts, my estimate… and the same headaches occured for her as if she had used a “natural cannaboid”. Since she can count the times she’s smoked pot on one hand, pretty much — and it didn’t “work” for her — and since she’s not a smoker by nature, either — the JWH-018 just “wasn’t her thing”.
It’s been my impression that OLD HANDS — folks of the Boomer Generation — are more likely to fall in love with this substance than your average Young Buck.
Hey Jason. In responce to how much we use. I find tolerance for myself is much greater than with weed…with me the tolerance seems to be almost as fast as opiates. But I find I reach an amount that seems to satisfy consistantly. When I first got this stuff.…I hadnt smoked pot in about 1 year. I did a poy seed sized amount and…oh shit man…I couldnt move, light hurt, I was drooling…sweating…I woke up like 5 hours late for work.…so.…I learned extreme caution.…it was Hell I thought I was going to die…on another time I gave a hit to a 55 year old lady friend. she was ok at first, then she like layed down on my bed, her hands and fingers curled up…and she cryed and begged for help for like 45 minutes…then puked…and passed out. I was really afraid she would die or something.…on that not.……RESPONSIBLE USE…and I highly doubt this will be sold at the gas station…as a matter of fact.…I KNOW it will be illegal soon as enough idiots get caught with it or start selling it on the street corner.…so get all u can…thats my motto..lol.….and Ive actually ate some in candy about four pot seeds worth…and it was awsome…it seems much more economic to smoke it though.…take care all synthetic caniboid explorers.
See, i need something that I could take and go to work with no problem. I can’t afford to have an adverse effect like this. Also, what about jwh-073, hu-200 and all of these other substances, has anyone tried them?
In July 2009, I went into my husband’s home office to find him slam in the middle of a grand maul seizure. I called the ambulance and at the hospital they gave him something introveniously. Who would have thought that would happen to him?
Hmmm…go ahead…do it again. Who knows what ONE TIME will do to you. Take a stand against crap like this. IT has to start somehwere.
Wanda: Please shed some more light on your husband’s experience. How much did he take? Was it pure, etc? Perhaps you could persuade him to come on here and explain the situation for himself?
Sorry to hear about Wanda’s husband… but when it comes to psychoactive substances, the genie is out now… so what should we do?
First, use reason/prudence/caution/respect about the substances we choose to use. Then we need to make sure we’re not going to harm anyone ELSE by what we’re doing.
Alcohol is, to me, the REAL “crap” that needs to be taken off the shelves — but it’s been around and been legal for … how long? People abuse it every day. ONE DRINK too many and it’s off the cliff you go… same with most other things — too much is NOT GOOD.
It’s not the booze or the dope that’s “the problem” usually as much as the person who uses it without educating themselves on what consequences they may likely/potentially face by its use. Mistakes happen, Ignorance happens — I know from personal experience!
And while I’ve had at least a few pretty wickedly BAD trips in my day, overall I think my life has been enhanced in positive ways from the experiences I’ve had, including those that didn’t kill me. When I find and know my limit for something I need to then take the responsibility to not cause myself a problem because over the limit is not good, either.
Well, if you want to swim in the ocean, you cant complain about getting stung sometimes.….
This is like most everything else, education is critical! Buy a milligram scale (.0001 accurate, $50 or so with some internet searching.
I see folks talking about “smoking” JWH 018. I highly recommend vaporizing.
Get a small appliance lightbulb.
Look at the end you screw into the socket. It has a shiny black surface with a tiny piece of wire in the center. Grab that bit of wire with pliers and pull out. Now that the black is cracked, you can chip it out, taking care not to tear up the soft aluminum of the bulb.
Once the black is completely gone, remove the lighting element (may have to tap it with anything long and skinny. All you want is a glass bulb with a hollow end.
I wrapped a bit of electrical tape around the threads (not needed).
If you do not have a scale, i suggest this. Use a BIC pen cap, and get a small pile, not more than 1mm worth, and pour this into the bulb.
I will say this, just hold the bulb upright and pour the powder in. It reminds me of small sand grains, it falls right to the curve of the bulb, maybe tap it gently with your finger to condense the pile.
Screw a 2 liter cap over the end of the bulb. It will fit loosely. I did this so the vapor wouldnt escape.
Now have a drinking straw handy.
For those unfamilar with vaporizing, you are not “burning” the product, you are releasing the vapors without burning the material.
Ok, here what to do and what will happen. I vape it in two parts. First part turns it froms a solid powder to a liquid.
Hold your lighter a good 2 inches below the pile and start adding heat. move the flame slowly closer until you see the powder start to liquify. Go slow, do not rush it. Once its a liquid puddle, stop adding heat!
It will solidify somewhat.
Now the vape begins. do the same with the lighter, 2 inches below, slowly move it up. Again go slow! as the flame get closer you will see the puddle start to give off vapor.Once it starts to give off vapor, try to stay the same distance from the bulb. move the lighter around the puddle to vape it all. Your bulb should be full of foglike smoke.
Once the vaping is done, quickly take the cap off, insert your straw, and inhale the vapors.
Sit back and enjoy!!!! You will feel a bit of tightness in your chest, so DONT PANIC!!!! It passes pretty quickly! I was fully expecting the chest tightness, and it still drew my attention.
Be responsible. I love to smoke pot, but honestly, if you smoke lesser quality, this stuff is definitely better!
Thanks everyone!
BTW, the JWH-018 is very indica like, but the JWH-073 is very cerebral, very sativa like, so go with your choice!
I imagine the two together would be fantastic!
I think jwh-073 is more for me then jwh-018. I love sativa! Has anyone else used jwh-073? I would like to know what effects people have gotten, and the recommended dosage.
i have just been given some jwh180 to try but not being funny it looks like it should go up the nose rather in a spliff.
if things have got that bad you would risk smoking that shit you need to talk to FRANK!!!!!
Whoa!! Don’t snort this stuff… just a bit of basic knowledge for those who may not know. I’d hate to even try to think what that might be like.
YIKES!!
I hear this stuff will be illegal in the UK from the 21st of December.
Dec 23rd, I think. The full ban is attached to the end of this post.
I bought a gram of pure jwh 018 from a friend and smoked it ‘heavily’ for about 2 months everyday.I am an old dope smoker who has smoked nearly everyday since 1969,so I am pretty experienced and i took LSD about 150 times in the 70’s.I found jwh to be far more than a marijuana substitute.In minute doses it is comparable to skunk.But it is very easy to get higher than you hoped for.In a slightly larger doses it is more like LSD,but without the paranoia that sometimes comes with LSD.The 2nd time I took JWH I did about 50 to 100 times too much and it was very scary.(I was drunk on beer and my judgment was impaired) I hallucinated wildly which was fun ‚but the other effects were unpleasant.My heart was pounding like it would jump out of my chest.I had cramps in my legs and arms and had cold sweats.I also got very paranoid and at times thought I was going to die !My wife ‚who doesn’t do drugs suggested I get fresh air and breath deeply ‚move about and think nice thoughts.It worked and I felt much better! So now I am much more careful and avoid it if I am drunk! I find that the intense high lasts about 2 – 3 hours but that I stay mildly high for the next 20 hours or so. One toke a day in the evening is enough.When I smoke skunk I usually do 5 or 6 smokes a day..So jwh is more economical and less harmful to my lungs I think.It also seems to be a clearer high,less goofy and less forgetful.So I would recommend it to any long term smoker but would say be careful !The effects creep up on you.It takes about 5 –10 minutes to get the full high.So it’s very easy to do too much.I would not recommend it to people who have little experience with hallucinagens as it might freak them out…
Important point made in the previous post… it does take 10 minutes or so for the full effects to kick in. And time can do weird things, like go too fast or slow than you realize is happening. Best to write down the time somewhere when you get started, and keep in mind to check the time now and then.
Newbies need to appreciate the advice of the previous poster in regards to a lack of experience with hallucinogens in general. Specificly, if one has previous experience with substances such as Salvia Divinorum and DMT — things what have quite a WHACK to them — it’s easier to go with the sudden transformation from being straight to totally… out there.
One 5-second hit of what I can Parslijuana (or “Pwanna”) the size of a small pea/pinch/16th teaspoon works wonders for a good amount of time and leaves one with enough motor ability to answer the phone, walk to the kitchen, etc.
It seems that ebay has blocked sales of this stuff. Where can someone buy this and how does one know how pure or impure it is?
I don’t think we’re allowed to post vendors, it’s just like average weed as far as effects go with me.
It’s pretty damn close, in fact..