Since my last post about the spice behind Spice (and other smoking muxtures such as Smoke, Serenity Now, K2, Sence, etc), it has been brought to my attention that some initial toxicology testing has been done on the synthetic cannabinoid JWH-018. Before we get down to the details however, here’s some pretty weird background information – the sponsor and provider of these studies wishes to remain anonymous! Unfortunately, this makes the whole thing a lot less credible, but since this is the only information we have right now, let’s hope someone else can verify these things at a later date. So far, one professor (who also wishes to remain anonymous) thinks these are real, but as of yet, no one is willing to put their name down on any kind of formal statement. If you, or anyone you know, has the relevant expertise to look over these studies, please drop me a line!
Feel free to invent your own conspiracy theories, but for now, let’s take a look at the data. You can download the PDF documents in this Zip file [2.04 MB]
CYP450 Inhibition Assay
This first assay looks at the effect of a drug on specific enzymes in your liver. These Cytochrome P450 enzymes are responsible for metabolising the vast majority of drugs you might put in your body, so if you’ve got too much of one drug in your system (ie paracetamol/acetaminophen), then other drugs that are also metabolised by these enzymes (ie alcohol) may compete for these enzymes and so hang around in your system for longer. As you can imagine, it’s important to understand how one drug may affect the metabolism of another, in case of any disasterous drug-drug interactions.
Results: JWH-018 will probably interact with the metabolism of other drugs, so more in vivo work is necessary.
hERG Binding Assay
hERG stands for human Ether-à-go-go Related Gene. This gene codes for a particular type of potassium channel found on heart tissue. This channel pumps potassium ions out of the heart muscle cells and are critical in coordinating the heart’s electrical activity. Unfortunately, these channels are a prime target for drugs to bind to, disrupting their function. This can lead to “Long QT Syndrome”, associated with fainting and can lead to sudden death, so you can see why these kinds of tests are important. Here’s a typical ECG recording showing what’s called the “QT interval” shown in blue, which lasts for longer than it should do if these channels are disrupted.
Results: JWH-018 does not interfere with these channels. That’s a good thing.
Cytotoxicity Assay
This simple test essentially looks at how many cells die when you perfuse them with a drug. The more cells that die, the more toxic the drug.
Results: JWH-018 is not cytotoxic at low concentrations.
GreenScreen HC Genotoxicity Assay
This assay looks at how much a drug will interfere with our DNA. Typically, anything that damages DNA is bad news, being potentially carcinogenic, making the rationale behind this test glaringly obvious. This test was also performed in the presence of a fraction taken from liver cells, which will break down the drug. This not only checks if the drug will damage DNA, but also its breakdown products.
Results: JWH-018 does not damage DNA, so shouldn’t give you cancer.
Rat Repeat Toxicity Assay
Guess what happens in this experiment. A number of renagade lab rats looking for a bad time are rounded up and promised free drugs (kind of like Pleasure Island from Pinocchio; that shit was scary!). The rats are then dosed up and observed. Initially, they appear lethargic (read: totally baked) but a few of them died at higher doses. This appears to be down to problems breathing rather than organ toxicity, but only affected the male rats, who appeared more sensitive to the compound. The drug didn’t appear to accumulate in their systems either, but they did lose some weight, probably because they couldn’t be arsed to eat. JWH-018 showed a huge potency and was found to be tachyphylactic (my new favourite word – it means that more of a drug is required to reach the same state following an initial dosage).
Results: According to FDA guidelines, the human equivalent dose is 0.016 mg/kg but it should be tested in other species before this can be seen as reliable!
Rat Pharmacokinetics
Data is collected on a number of different “pharmacokinetic” aspects of the drug, such as how it is absorbed, distributed throughout the body, metabolised and excreted, which can help with the design of future clinical trials.
Results: JWH-018 is distributed well throughout the rat’s tissues. Metabolism and excretion are normal, with a plasma half-life of approximately 2 hours
Summary
Well, from the looks of these tests, JWH-018 seems to be pretty safe, but unless you want to piss off Ben Goldacre, it would be wise not to rely on this “test tube data” entirely. Also, like I said before, we don’t know where this data has come from, clouding the issue even further.
Feel free to ask any questions in the comments.
Big thanks to Alfa @ Drugs-Forum.com for letting me know about these studies. You can read all about JWH-018 on their Drugs Wiki.
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Friday, 3. July 2009
Would jwh-018 show up as THC in a urine,blood,hair folicule test? Since this is a relitively new compound. How much testing is actually being done on it? I wish somone with some credibility would be able to do some testing on this.
Saturday, 4. July 2009
No, it won’t show up on a normal drug test.
The only similarities between this and THC are the receptors they both bind to.
Friday, 14. August 2009
After haviing found Bad Science, I think I should change my homepage! By luck I happened to find it by posting the link to this page on my website.
If I was on a desert island with just portal… give me more Bad Science!
But Science is good… and getting better. Just look what they can do with chemicals nowdays. Research continues.
Saturday, 15. August 2009
Whether a drug is dangerous or not will not make any difference to the government in deciding whether to ban it. If it gets you high, in their minds, it is bad. If it is not dangerous, they will simply lie to people and tell them it is dangerous and ban it anyway.
Sunday, 16. August 2009
The Gov’t wants to collect TAXES more, I think, than just about anything. They allow dangerous drugs and activities to remain legal in order to get tax revenue, despite the known risks.
People ALWAYS will want to gain cosmic insights, get loaded, zone out, get laid, and have adrenaline rushes… and will take whatever measures they feel necessary to get them.
If the Gov’t wants to declare JWH-018 as a danger to what — society? – then they can sure outlaw it, for what it’s worth to do so. The “War On Drugs” will continue — and to MY way of seeing things — THAT’S the REAL danger!!
Monday, 17. August 2009
regardless of its safety it may be it is not a patch on the real thing.Its like comparing rough cider to champagne.Personally i think the synthetic cannabis products are horrible and fail to see what the point is unlesss you are real desparate to get high.My advise if you can’t thec real thing do some cardia vascular excerise or yoga and do’nt waste your money on such awlful products
Tuesday, 18. August 2009
Chris (& possibly Tim): You might like to have a read of this post about religion’s role in keeping drugs illegal.
Motlly: Luckily, a lot of people disagree! In fact, some people prefer them to cannabis. I guess they’re also useful if all you can get hold of is shitty soapbar as sam commented on Can I Get High Legally?.
Tuesday, 18. August 2009
Thanks for the links, Synchronium.
For my opinion to count in the world, I have to make it known somehow. And my opinion is that whatever results in the least amount of harm, to the most people, is a GOOD THING.
Keeping natural substances illegal increases the incidence of violent crime, ruined relationships and lost opportunities pretty much any way you cut it — in MY book. Anyone who can defend a “War On Drugs” HAS to be messed up!
The beauty of a substance like jwh-018 is that its capable of giving people what they want, at a lower cost, in a pure form with a set dosage, and less apparent health risks, too.
It can be regulated by taxation, and since not everyone can or wants to produce it (as compared to throwing some weed seeds in the dirt) there’s less chance of a violent black market springing up if responsible parties are trusted to produce it under laboratory conditions.
If there’s no way to ELIMINATE risks of inevitable human activities and desires — why not take the next best step and minimize them as much as possible? As much as the conservatives and religious right would have otherwise… the simple truth is the genie is out of the bottle and ain’t about to climb back in.
Saturday, 5. September 2009
I passed a hospital drug screen having smoked a jwh-018 fortified herbal blend daily for about a week before the test. JWH-018 will not cause you to fail a drug test.
Tuesday, 15. September 2009
im on probation and i think it would take them months to figure out the what they were looking for. my inpute on jwh-018 four stare high. synthetic supplys has a very good herbal mix called budda blend for a great price 5 grams for 30 dollars.stronger than pep spice spice gold ect……..
Tuesday, 15. September 2009
they cant win the war on drugs anyway!
Wednesday, 16. September 2009
I have been smoking an herbal blend called Stryker for about a week now. I have noticed some lower back stiffness and aches-could this be related? I’m a little scared, as the package was totally shady, no ingredients listed, no manufacturer name-NOTHING!
I do have to say though, this herbal blend, much like Serenity Now Herbal incense, is totally intense and very long lasting! If anyone has had any similar side effects, please post!
Sunday, 20. September 2009
personally i like it..medically its good to kno about some of this stuff .. and i always have some to share..
Saturday, 26. September 2009
My sons friend just smoked some jwh-018 that he purchased on ebay and is now in the emergency room and can’t breath on his own,,this stuff is really dangrous
Tuesday, 29. September 2009
Yes jwh is Toxic….
Only after 5 year of abuse.
its come to the surface…
If you want to use 018.
then go ahead.
but let me tell you.. in the end, you will give it up
Tuesday, 29. September 2009
Spaced out: Perhaps you know something we don’t. Got any sauce for those facts?
Wednesday, 30. September 2009
My wise old daddy told me years and years ago that “Too much of ANYTHING is not good” — and I believe him.
What constitutes Jwh-018 “abuse”? Once a day? Or week? Wake and bake and stay loaded all day, day in and day out? Guess we all have to determine that for ourselves.
As with any other substance/drug, it can indeed be dangerous or even deadly, I suppose… even as if you were to consume too much WATER it could kill you, too. The problem with this chemical is that it is effective in such TEENSY TINY quantities that incautious people will inevitably sometimes take too much and get wigged out from it.
Know your tolerance and know your doseages, and take care!
Friday, 2. October 2009
its considerably nore potent that thc, if you like did a hot knife with it or something it would be like taking loads of hits of pure thc oil all at once, you have to dilute it or you will overdose and end up in a bad state, like if you smoke waaaaay too much weed i guess…
Saturday, 3. October 2009
I wonder what the effects are when the substance is used in a vaporizer?
Saturday, 3. October 2009
I’ve now had a number of experiencea with JWH-018. Personally, I love it. I’m on probation and this is the only way I was able to comfortably quit smoking weed. I find the buzz to be identical to marijuana at loto moderate doses but the main problem is dosing correctly. Without a milligram scale it can be very east to put out too much. A couple people around town and I have experienced a high dose and its not very pleasant. Whatever you do, be careful because it can cause panic attacks and difficulty breathing. We found that a mound about the size of a pot seed is a good dose to start with. Once you grow a little tolerance to it then you can dose a little higher. In the event that you do dose too high, don’t freak out and don’t fight it. It’s stronger than you. The best thing to do is just sit back and go along for the ride until you can grasp it. Best of luck and be careful.
Saturday, 3. October 2009
Can I fail a drug court test by smoking Serenity Now Herbal Incense? Feels like I smoke that good and I do not want to piss for these people and have to do 30 days ………like asap
Sunday, 4. October 2009
ya watch e-bay, my pet monkey got JWH-018 200 mg’s and and when he ran out to the mailbox 2 days later it was there! but.. it was prolly only 30-50% pure, this is the dangerous part, not truly knowing how much to put in when the batch is “cut”, be careful, but i can also say since i was raided for 26 plants, (all attitude feminized seeds, 10 white dwarfs were ready for harvest, and the others were in 3 weeks bloom, white widow ss haze, etc…fox farm certified!) errrrrrrrrr anyway i have very little money and have found it nice to buy a couple gram of cannibus and a sizable amount of jwh-018, jwh-073 w/e theres now 2 more also. anyways its nice to mix a hit or two of real cannibus with 018 to get a lil more than a meranol effect (thc pill) very cerebral and nice by itself, but feels more comrortable with some real erb, this is a cheap way to stretch a budget if you have true nausea/pain issues like me. unfortunately im from the states and there is no herbal blends i know of here, im sure when or if im tried (idk wuts goin on at the moment as i do have serious medical ailments) i will find an herbal blend instead of just smokin some powder on a cigg, those herbal blends all range in types of jwh’s and have other weaker cannabanoid receptor attaching chems. in them, i here it is a good way to go if you know a good vendor for a spice that says whats in it. I don’t know any. my monkey wants to know though, he liked my plants to.
Sunday, 4. October 2009
Serenity Now is Awesome, and I passed my drug test just fine! If you are scared just go to the drug store and get an at home test to ease your mind.
Monday, 5. October 2009
What is PARSLIJUANA?
Just a word I made up for 500 MG of JWH-018 mixed in with 5 grams of dried parsely flakes soaked until dry in a cup or so of 95% EverClear.
Almost makes one want to register the domain name, hmmm??
Wednesday, 7. October 2009
JWH-018 Is an excellent ‘drug’ – First few times of use will be like very similar to what most cannabis ‘users’ experienced. Very very stoned feeling, Maybe not fully enjoyable? But you learn to enjoy it more and I guess you nearly instantly build up a small tolerance to where you can enjoy it.
My experiences with this JWH-018 was nearly mirror’d as if i was taking weed for the first time.
As a 10 year cannabis smoker (daily) I enjoyed it, But After just one day of using jwh-018, rapidly built up a big tolerance to this, Exactly the same as weed/skunk what ever
But yeh, Nice to experience. Also nice to mix with weed or smoking blends.
I cant see any one going to hospital over this or anytihng. I smoked very high doses of it, Just ended up as if I smoked like half ounce of decent weed, monged out, needing food/water, Proper felt same for the following morning.
I rate it highly, Sad thing is the tolerance Issue.
I’m going to try out the other jwh-xxx’s – See what they’re saying!
Oh yeh nice site btw!
Wednesday, 7. October 2009
does anyone know if smoking blends like spice gold, smoke xxx that contain jwh everyday for a year cause some kind of cancer? and is jwh o18 safe to use or deadly? ive been hearing different things about this so i thought id ask.
Thursday, 8. October 2009
Recently I ordered 5 grams of JWH-018 from [THE INTERNET]. The product came in 3 days and was of the highest quality and a good price. I gave a few of my friends some doses and told them how to safely dose yourself. Unfortunately, they gave some to friends too and didn’t explain the dosages and someone ended up going to the hospital because they thought they were going to die. Since they got it from someone who got it from someone, they didn’t know the proper name for it and the hospital thought they were given ghb. The girl was fine after about an hour but a lot of questions are now being asked. This stuff is awesome, but it’s no joke.
Thursday, 8. October 2009
You can find JWH-018 of equal quality for considerably less if you look around… or even free (10MG) samples of it at [ANOTHER WEBSITE ON THE INTERNET]. I’ll be the first to agree, though, that this “awesome stuff” is definately “no joke”.
With that in mind, my advice is to make the straight chemical into a standardized, easy to use form that you can share with others that won’t get them in the emergency room to do ignorance of how to use it. The original “parslijuana” I made was toooo strong, so it was diluted to about 7 grams of parsley to 500 MG of JWH-018, soaked in a cup of 95% Everclear grain alcohol until dry.
This way, if shared with others, the instructions are “Take ONE hit every 1-2 hours as desired”. Those with a pre-existing tolerance buildup could manage two hits back to back… but most people (IMHO) will realize within 2-3 minutes that a single hit is all that is needed… or desired.
Friday, 9. October 2009
Hey all…..
UK readers might be interested in the following report to the Home Secretary from the Advisory Council on the Misuse of Drugs:
http://drugs.homeoffice.gov.uk/publication-
search/acmd/acmd-report-agonists?view=Binary
In addition, there’s an interesting link on the following page from the European Monitoring Center for Drugs and Drug Addiction regarding their recomendations for the control of Spice and synthetic cannabinoid agonists such as the JWH group:
http://www.emcdda.europa.eu/attachements.cfm/att_80086_EN_EMCDDA_Understanding%20the%20‘Spice’%20phenomenon_4Update%2020090813.pdf
The following was of special interest:
“The Commission-funded Psychonaut web mapping project continuously monitors the web for novel
compounds, using 9 languages, with the support of different tools/software (e.g. Google Insight, Blue Crab,
Boolean Search, InSite, Advanced Web Ranking and SerpSpy). The project monitors regularly more than
200 websites, forums and blogs which provide information on many compounds”
Hope I’ve not bored you all too silly….
Saturday, 10. October 2009
in a hospital blood scan. will serenity now contents show up ? and what will it show up as? i understand it wont show up in a piss test becuase the piss test would have to know what its looking for. but what about a full blown hospital blood scan that they give for a “on the job accident” , etc.
Sunday, 11. October 2009
HairyCelt, that is very interesting stuff! I skimmed through it, and found it to be very interesting but really technical. Right now I am resorting to using ginko biloba mixed with piracetam to get my cerebral fix. This combination creates clear mindedness and alertness. I wish there was a legal substance that I could vaporize with no trouble.
Friday, 23. October 2009
I have over the used used forums like this in my exploration of drugs. So now I will give back. I have been doing JWH-018 for about 7 months now. The only thing that would give me a clue that I wasnt smoking weed is the way JWH is smoked. Other than that, to me, its like dank nugs. I am 34 and smoked since 14….steadily. I was your typical pot head. Then as a result of a divorce and a narc wife, I had to quit pot…for my kids sake…I have custody. Well, I have had 2 piss test at work. Taken at a hospital, passed, no questions, 1 piss test for court, Redimed…Passed….I was injured at work=workers comp….Passed. It is safe to say you can pass test with no worries. I have went through about 8 grams now…I love it.As with any drug…responsible use, caution and respect will prove useful and ensure the fact that you can now be high all you want…and they cant even prove it. In closeing, I use a very small wire with a flat end…very very small…I find with no scales…this wire will only alow me to pick up a minimal amount at a time…but Ill just shut up now…..DAMN I LOVE JWH>HE should have gotten the nobel peace prize….
Friday, 23. October 2009
Rather interesting to read how many people post about the JWH-018 and use terms as “I love this stuff”, “my beloved JWH” and such.
Seems like more people have found it to be of benefit than have gotten freaked out about it. Most everyone also mentions using it RESPONSIBLY — which should be a no-brainer with ANY substance/drug — but still, is good advice for Newbies.
Some will love it, for sure, and those who hate it just don’t like drugs or something, I guess. The drugs/drugs effects aren’t “the problem” with most drugs as much as the person who abuses them, eh?
Seems unlikely that NarcoTerrorists are gonna be gunning people down in Detroit to sell this stuff, so no problem there, either. Shucks, I wouldn’t even mind paying State sales tax on it if they/The Govt allowed it to be sold at the corner 7-11 at a resonable price.
Why not?
Saturday, 24. October 2009
Hey everyone, my second post. I am reading the actual patent for this stuff and I am reading some interesting elements as such:
quote “DESCRIPTION OF SOME PREFERRED EMBODIMENTS
As used herein, a “therapeutically effective amount” of a compound, is the quantity of a compound which, when administered to an individual or animal, results in a sufficiently high level of that compound in the individual or animal to cause a discernible increase or decrease in stimulation of cannabinoid receptors. Physiological effects that result from cannabinoid receptor stimulation include analgesia, decreased nausea resulting from chemotherapy, sedation and increased appetite. Other physiological functions include relieving intraocular pressure in glaucoma patients and suppression of the immune system. Typically, about 10 mg/day to about 1,000 mg/day is a possible “therapeutically effective amount” for the inventive compounds. ”
10 mg per day… how much are you guys using?
The compound of the present invention can be administered by a variety of known methods, including orally, rectally, or by parenteral routes (e.g., intramuscular, intravenous, subcutaneous, nasal or topical). The form in which the compounds are administered will be determined by the route of administration. Such forms include, but are not limited to, capsular and tablet formulations (for oral and rectal administration), liquid formulations (for oral, intravenous, intramuscular or subcutaneous administration) and slow releasing microcarriers (for rectal, intramuscular or intravenous administration). The formulations can also contain a physiologically acceptable vehicle and optional adjuvants, flavorings, colorants and preservatives. Suitable physiologically to acceptable vehicles may include, for example, saline, sterile water, Ringer’s solution, and isotonic sodium chloride solutions. The specific dosage level of active ingredient will depend upon a number of factors, including, for example, biological activity of the particular preparation, age, body weight, sex and general health of the individual being treated.
So obviously, according to the patent, we don’t have to risk getting cancer by smoking it, we can actually use it topically on the skin and get an effect, or mix it in a liquid and drink it? Smoking is probably the worst way of using this stuff.
Here are my main concerns before attempting to try this stuff.
1) How can a person verify that the stuff they purchase is really pure? Which vendors are the best?
2) How can a person actually measure out 10, 20 or 30 mgs of the stuff?
3) Has anyone used this stuff in a method other then smoking it? I would be interested in vaporizing.
keep these posts rolling, knowledge is power,
btw, if you want the patent link here it is:
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=7241799.PN.&OS=PN/7241799&RS=PN/7241799
Saturday, 24. October 2009
I know a fellow who uses JWH-018 orally and reports real good results from it. Dose size is unknown exactly, but estimated 5-10 MG. He says he’s never had a “bit too much” using it that way as compared to smoking it — where even a little “too much” can bring on undesireable side effects.
My wife has tried it orally both in about 3-6 MG amounts, my estimate… and the same headaches occured for her as if she had used a “natural cannaboid”. Since she can count the times she’s smoked pot on one hand, pretty much — and it didn’t “work” for her — and since she’s not a smoker by nature, either — the JWH-018 just “wasn’t her thing”.
It’s been my impression that OLD HANDS — folks of the Boomer Generation — are more likely to fall in love with this substance than your average Young Buck.
Saturday, 24. October 2009
Hey Jason. In responce to how much we use. I find tolerance for myself is much greater than with weed…with me the tolerance seems to be almost as fast as opiates. But I find I reach an amount that seems to satisfy consistantly. When I first got this stuff….I hadnt smoked pot in about 1 year. I did a poy seed sized amount and…oh shit man…I couldnt move, light hurt, I was drooling…sweating…I woke up like 5 hours late for work….so….I learned extreme caution….it was Hell I thought I was going to die…on another time I gave a hit to a 55 year old lady friend. she was ok at first, then she like layed down on my bed, her hands and fingers curled up…and she cryed and begged for help for like 45 minutes…then puked…and passed out. I was really afraid she would die or something….on that not…….RESPONSIBLE USE…and I highly doubt this will be sold at the gas station…as a matter of fact….I KNOW it will be illegal soon as enough idiots get caught with it or start selling it on the street corner….so get all u can…thats my motto..lol…..and Ive actually ate some in candy about four pot seeds worth…and it was awsome…it seems much more economic to smoke it though….take care all synthetic caniboid explorers.
Sunday, 25. October 2009
See, i need something that I could take and go to work with no problem. I can’t afford to have an adverse effect like this. Also, what about jwh-073, hu-200 and all of these other substances, has anyone tried them?
Monday, 26. October 2009
In July 2009, I went into my husband’s home office to find him slam in the middle of a grand maul seizure. I called the ambulance and at the hospital they gave him something introveniously. Who would have thought that would happen to him?
Hmmm. . .go ahead. . .do it again. Who knows what ONE TIME will do to you. Take a stand against crap like this. IT has to start somehwere.
Monday, 26. October 2009
Wanda: Please shed some more light on your husband’s experience. How much did he take? Was it pure, etc? Perhaps you could persuade him to come on here and explain the situation for himself?
Tuesday, 27. October 2009
Sorry to hear about Wanda’s husband… but when it comes to psychoactive substances, the genie is out now… so what should we do?
First, use reason/prudence/caution/respect about the substances we choose to use. Then we need to make sure we’re not going to harm anyone ELSE by what we’re doing.
Alcohol is, to me, the REAL “crap” that needs to be taken off the shelves — but it’s been around and been legal for … how long? People abuse it every day. ONE DRINK too many and it’s off the cliff you go… same with most other things — too much is NOT GOOD.
It’s not the booze or the dope that’s “the problem” usually as much as the person who uses it without educating themselves on what consequences they may likely/potentially face by its use. Mistakes happen, Ignorance happens — I know from personal experience!
And while I’ve had at least a few pretty wickedly BAD trips in my day, overall I think my life has been enhanced in positive ways from the experiences I’ve had, including those that didn’t kill me. When I find and know my limit for something I need to then take the responsibility to not cause myself a problem because over the limit is not good, either.
Wednesday, 28. October 2009
Well, if you want to swim in the ocean, you cant complain about getting stung sometimes…..
This is like most everything else, education is critical! Buy a milligram scale (.0001 accurate, $50 or so with some internet searching.
I see folks talking about “smoking” JWH 018. I highly recommend vaporizing.
Get a small appliance lightbulb.
Look at the end you screw into the socket. It has a shiny black surface with a tiny piece of wire in the center. Grab that bit of wire with pliers and pull out. Now that the black is cracked, you can chip it out, taking care not to tear up the soft aluminum of the bulb.
Once the black is completely gone, remove the lighting element (may have to tap it with anything long and skinny. All you want is a glass bulb with a hollow end.
I wrapped a bit of electrical tape around the threads (not needed).
If you do not have a scale, i suggest this. Use a BIC pen cap, and get a small pile, not more than 1mm worth, and pour this into the bulb.
I will say this, just hold the bulb upright and pour the powder in. It reminds me of small sand grains, it falls right to the curve of the bulb, maybe tap it gently with your finger to condense the pile.
Screw a 2 liter cap over the end of the bulb. It will fit loosely. I did this so the vapor wouldnt escape.
Now have a drinking straw handy.
For those unfamilar with vaporizing, you are not “burning” the product, you are releasing the vapors without burning the material.
Ok, here what to do and what will happen. I vape it in two parts. First part turns it froms a solid powder to a liquid.
Hold your lighter a good 2 inches below the pile and start adding heat. move the flame slowly closer until you see the powder start to liquify. Go slow, do not rush it. Once its a liquid puddle, stop adding heat!
It will solidify somewhat.
Now the vape begins. do the same with the lighter, 2 inches below, slowly move it up. Again go slow! as the flame get closer you will see the puddle start to give off vapor.Once it starts to give off vapor, try to stay the same distance from the bulb. move the lighter around the puddle to vape it all. Your bulb should be full of foglike smoke.
Once the vaping is done, quickly take the cap off, insert your straw, and inhale the vapors.
Sit back and enjoy!!!! You will feel a bit of tightness in your chest, so DONT PANIC!!!! It passes pretty quickly! I was fully expecting the chest tightness, and it still drew my attention.
Be responsible. I love to smoke pot, but honestly, if you smoke lesser quality, this stuff is definitely better!
Thanks everyone!
BTW, the JWH-018 is very indica like, but the JWH-073 is very cerebral, very sativa like, so go with your choice!
I imagine the two together would be fantastic!
Wednesday, 28. October 2009
I think jwh-073 is more for me then jwh-018. I love sativa! Has anyone else used jwh-073? I would like to know what effects people have gotten, and the recommended dosage.
Sunday, 1. November 2009
i have just been given some jwh180 to try but not being funny it looks like it should go up the nose rather in a spliff.
if things have got that bad you would risk smoking that shit you need to talk to FRANK!!!!!
Sunday, 1. November 2009
Whoa!! Don’t snort this stuff… just a bit of basic knowledge for those who may not know. I’d hate to even try to think what that might be like.
YIKES!!
Thursday, 12. November 2009
I hear this stuff will be illegal in the UK from the 21st of December.
Friday, 13. November 2009
Dec 23rd, I think. The full ban is attached to the end of this post.
Tuesday, 17. November 2009
I bought a gram of pure jwh 018 from a friend and smoked it ‘heavily’ for about 2 months everyday.I am an old dope smoker who has smoked nearly everyday since 1969,so I am pretty experienced and i took LSD about 150 times in the 70’s.I found jwh to be far more than a marijuana substitute.In minute doses it is comparable to skunk.But it is very easy to get higher than you hoped for.In a slightly larger doses it is more like LSD,but without the paranoia that sometimes comes with LSD.The 2nd time I took JWH I did about 50 to 100 times too much and it was very scary.(I was drunk on beer and my judgment was impaired) I hallucinated wildly which was fun ,but the other effects were unpleasant.My heart was pounding like it would jump out of my chest.I had cramps in my legs and arms and had cold sweats.I also got very paranoid and at times thought I was going to die !My wife ,who doesn’t do drugs suggested I get fresh air and breath deeply ,move about and think nice thoughts.It worked and I felt much better! So now I am much more careful and avoid it if I am drunk! I find that the intense high lasts about 2-3 hours but that I stay mildly high for the next 20 hours or so. One toke a day in the evening is enough.When I smoke skunk I usually do 5 or 6 smokes a day..So jwh is more economical and less harmful to my lungs I think.It also seems to be a clearer high,less goofy and less forgetful.So I would recommend it to any long term smoker but would say be careful !The effects creep up on you.It takes about 5 -10 minutes to get the full high.So it’s very easy to do too much.I would not recommend it to people who have little experience with hallucinagens as it might freak them out…
Thursday, 19. November 2009
Important point made in the previous post… it does take 10 minutes or so for the full effects to kick in. And time can do weird things, like go too fast or slow than you realize is happening. Best to write down the time somewhere when you get started, and keep in mind to check the time now and then.
Newbies need to appreciate the advice of the previous poster in regards to a lack of experience with hallucinogens in general. Specificly, if one has previous experience with substances such as Salvia Divinorum and DMT — things what have quite a WHACK to them — it’s easier to go with the sudden transformation from being straight to totally… out there.
One 5-second hit of what I can Parslijuana (or “Pwanna”) the size of a small pea/pinch/16th teaspoon works wonders for a good amount of time and leaves one with enough motor ability to answer the phone, walk to the kitchen, etc.
Thursday, 19. November 2009
It seems that ebay has blocked sales of this stuff. Where can someone buy this and how does one know how pure or impure it is?
Thursday, 19. November 2009
I don’t think we’re allowed to post vendors, it’s just like average weed as far as effects go with me.
It’s pretty damn close, in fact..
Saturday, 21. November 2009
Ok. I’ve read many questions and only one brief answer about what exactly jwh-073 does and how it compares to jwh-018. I like the 018 A LOT. I have to take drug tests, and I think it’s even better than weed and so glad I discovered it. Although, weed is the only thing I can compare it to. I can see how it would be similar to acid if you smoke too much, like everyone has already said. But if you just do the little bit and gradually build your tolerance, I love it! It only made me paranoid and super ripped the first time, mainly because I think I was so wigged out about what it even was and how it wouldn’t show up on a drug test, which is hasn’t. But what’s with the 073. I read a post that said 018 is like indica and 073 is more like sativa, but I need that broken down in a little simpler terms. Any advice would be helpful!
Saturday, 21. November 2009
Indica is a body high, or body buzz. Usually relaxes your body , muscles, etc. Sativa is more of a mind buzz, cerebral. Personally, I prefer sativa because it stimulates my imagination, and creativity. It seems that I am more focused and I do everything better. Indica makes me really lazy and puts my brain in a fog and makes me less productive.
Monday, 23. November 2009
Mr Skunk thinks that 073 is very nice except the fact it only seems to last about an hour, and it gets pretty more-ish. It was enjoyed, but it goes MUCH faster than 018 making it a lot less economical. 5mg 018 and 10mg 073 is a very nice buzz for Mr Skunk.
Monday, 23. November 2009
Re the previous message… would one be able to use the 10 MG of 073 orally with good results, or is that a smoked amount?
Saturday, 28. November 2009
I’d just like to correct the end of Ben Hailey’s wonderful post as he mixed the -018 and -073 up, for the record it is the -018 that is the sativa high and the -073 that is an indica high.
-018 is about three times the potency of -073. a 1 to 3mg dose of -018 like any sativa is a very heady, psychedelic, creative, buzzy brain high and can be incredibly aggressive and unforgiving with even 1 mg too much.
A 3 to 9mg dose of -073 like any indica is a more sedating, sleepy, body high with analgesic properties, it’s highly unlikely one would panic on typical doses of -073 due to the nature of this compound, it’s kind and mellow.
Most people I’ve come across prefer -073 but tend to build up tolerance very quickly and thus use it up very quickly.
A combination of one part -018 and three parts -073 is a perfect mix.
Find a plethora of experience reports relating to JWH-015, JWH-018, JWH-073, JWH-081, JWH-200, JWH-250 at drugs-forum.com
Do your homework before messing around with JWH-018, this is not cannabis, it’s an INCREDIBLY powerful synthetic chemical and a .001mg scale is essential.
Friday, 4. December 2009
And I return again. I went through 5 grams in about 2 months. Ive been out for 2 months and got more today. Wow, its like geting high for the first time. My point being, rapid tolerance is the bigest issue for me. I will try to limit it to only late night use…though like crack…you just wanna feel this good all the time. I have found a light bulb the BEST way. Previously I burned it in a pipe on ash…except for the cost of lighters…vaporizing seems much more economical….ive done a total of 7 1/2 grams of this shit now…and feel im pretty experienced…so once its Illegal here in USA…I can say I did it….also…yes the guy that compared it with acid….Dude it is at high doses. Be careful everyone…and enjoy it…they will take it from us soon.
Friday, 11. December 2009
i have been smoking jwh-018 for a while now. i recently learned that a guy i know died after smokin this. he went to lay dowwn for a nap and never woke up. they think he quit breathing in his sleep. this stuff is dangerous and people smokin it should definately know their dosage. please be careful
Saturday, 12. December 2009
I smoked about 100 mg over the course of 2-3 days. It is very strong stuff, scary…. affects the body too much ( I was scared I was gonna die) and I had a little trouble breathing the next day ( I do have asthma)
It does get you blasted, be very careful if you experiment. Just do a tiny tiny bit and resist the temptation to keep getting loaded multiple times in a night like I did.
Saturday, 12. December 2009
While I definitely concur with the “know your dosage” caveat, it seems kind of strange to me that someone would go to sleep while under heavy effects of Jwh-018…?
Maybe it’s just me, but it tends to energize me for the first hour or so after use — hardly sleepy!
On the learning curve towards getting to know the Sweet Spot dosage I did sort of overdose somewhat a few times… and those episodes we’re intense (and scary) enough to keep me waaay awake until they subsided.
JWH-018 is dangerous to use with caution and respect, for sure.
Thursday, 17. December 2009
In China when you want to buy weed, all they usually sell is “hash” but in actual fact China is the largest producer of JWH, so it’s usually substituted with JWH, but they still call it hash.
So it’s the most common drug around over there, at least in some areas. With their harsh laws and punishments(execution) I guess it’s safer to sell JWH and tell everyone it’s cannabis. They cut it with THC and pollen from the low potency wild native cannabis strains sometimes, or with just random stuff… anyway, you can tell that it is JWH since it’s orally active, whilst THC needs to be bonded with oil/fat molecules to be readily absorbed by the body. I know several people who tried it orally, they say the high was long lasting and said there were no ill effects, by the sounds of it the effect was fairly mild though. They didn’t even take a measured dosage. But I think all the JWH sold on the streets in China is cut. You can get pure stuff in bulk from manufacturers over there though.
If you want to test whether it’s pure, I heard from an semi-reliable source that you can dissolve it in water. Pure JWH should dissolve completely(no sediments/particulates visible at all) and then revert back to a crystaline state when the water is evaporated off. But I haven’t tested or verified this. I know it does dissolve in isopropyl alcohol though.
The powder should also be white or slightly off white. The less white it is the more impure it probably is. But it can be cut with white powders, so looking closely at it you will see that it is sparkly and crystalline like sugar or salt, not dull like ajax haha. So if it’s white but isn’t a bit sparkly in direct light, then it’s probably cut with chalk or something…
Tuesday, 22. December 2009
according to everything else i have read, it is not soluble in water or even alcohol with more than about 25% water content…
as i understand it, it is best dissolved in acetone to lay it on something …at least the chemistry majors think so.
i have also heard of good results with everclear and 151…but you have to agitate it and heat the alcohol in a hot water bath a bit to make it dissolve completely.
i have also seen reports of recrystallization when this alcohol was cooled, so it would seem that alcohol has it’s limits.
at least if you use acetone to lay it on, it will completely evaporate; and you can’t miss it when it has because it’s odor is so pungent.
personally, acetone worries me a bit…i think i’ll stick with everclear.
Saturday, 2. January 2010
I’ve been bonging JWH-018 on top of a pile of Spice for the last few months. I have high body weight and high tolerance so I smoke about 4-5 mg at a time and this gets me as baked as you’d ever wish to be.
I recently accidentally overdosed (long story, my own stupid fault) on about 8-10 mg and had an incredibly nasty experience that involved projectile vomiting, temporary blindness, rivers of cold sweat, shaking, waves of fire sweeping through my body, and losing sense of who I was or what was going on. It was pure torture for about an hour, and I was in so much physical and mental pain that I prayed to die or be released.
Please guys, don’t make the same mistake I did. I’ve found JWH-018 wonderful when used respectfully and cautiously. But throw caution to the wind one time, and this stuff will not go easy on you!
Monday, 4. January 2010
I’ve gotten to the point where my attitude is pretty much “you can’t do TOO LITTLE” when it comes to the Jwh-018.
Even teensy amounts seem to have SOME effect — while teensy amounts TOO MUCH will have WAY too much oomph. I concur with CHRYSALIS — go easy with this stuff. Know your “sweet spot” and don’t think that just a little bit more is ok!
Once you’ve had a taste of The Fears, you’ll likely learn… the hard way.
Monday, 4. January 2010
I see all of these comments about this stuff and find it very interesting. However I think that it is extremely unfortunate that very very very little is known about the long term affects of this substance. I think we should put our money together and high a scientist to find out the long term effects of this stuff so we’ll all know and want be ignorant!
Monday, 4. January 2010
Jason: The problem with finding out the long-term effects of a substance is that it takes…a long time. And now it is illegal in the UK, and as we have recently seen, politicians aren’t massive fans of the truth, especially when it clashes with their established drug policy.
Making it illegal will make getting funding to get funding and licenses to experiment with JWH more difficult.
So the Government have it set on two levels: 1) By limiting research on JWH they prevent information about it arising which could challenge their position; 2) As we have seen, even when pertinent information is present, they ignore it anyway!
As for putting out money together, its a nice idea, but would require one or more of us to be extremely wealthy, as extended trials of this kind, even in rats, cost an extraordinary amount.
Tuesday, 5. January 2010
Ive smoked roughly all the spice blends and conclude that pep spice is the best alternative to thc. The main ingredient is lactuca virosa. It states all the ingredients on the package as is very relaxing.Lactuca virosa is a wild lettuce that when cut , secretes out its magical source of a legal high. Just like poppys do. Wildly grown in britain. Legal in the us. Those of you that state jwh-018 made someone you know go to the hospital and couldnt breath , must have either done something else or have had some lung condition that requires no smoking, because ive smoked it for a 4 month period 5 times a day everyday. Jwh-018 is as good but id consider pep spice because of the replicated high to that of some good med marijuana high.
Wednesday, 6. January 2010
I have smoked JWH around thirty times so far. It is great
in small amounts, leaves you “high” for several hours and makes your feel awesome. As far as the woman with a kid in the ER, sorry your son was a moron who more than likely smoked tons of JWH to show off to his friends, this stuff is plainly labeled and sold for adult use only. I heard many stories from teens who claim to smoke Salvia Devinorum in large quantities. Kids should not to using “Drugs” by any means. I have not seen any effects in myself other than a expansion of myself intellectually, maybe a slight decline in motivation, but it is winter right now. I think it’s great for people who have to take drug tests and still want to watch a buzz from time to time and not worry about losing their job or going to jail. Great stuff!!!
Sunday, 10. January 2010
what about red dawn spark gold ???? any reviews???
Tuesday, 12. January 2010
Do u just mix jwh in to batch as blending or is there more to it?I just ordered diferent herbs.
Tuesday, 12. January 2010
This stuff is kind of awkward when smoked with other ppl. It seems almost as if a mood enhancer that works as a collective energy among the ppl you are around. I would describe as coming on like the body buzz after Salvia then slowly morphing similar to rolling. This is Serenity Now, gold pack. Odd stuff, even in small doses it is very potent, different buzz entirely. Very strong
Wednesday, 13. January 2010
so i have tried “serenity now” couple nights ago and had the worst trip ever. i occiasonaly smoke pot and tried serenity with my buddy. i felt as if i couldnt breathe and my heart was beating really fast. for some reason now i feel as if somthing is missing in my head, kinda have a hard time sleeping at times and concentrating. so my question is, are there any long term side effects of this drug???? anything to worry about or will it just go away??
Thursday, 14. January 2010
I know what you mean about the small anxiety at the onset, nothing to panic, use in moderation, don’t smoke it like it is marijuana. I can’t see any long term side effects over the 3 months I have used the “spice” blends and it has not been around long enough for these effects to be accurately tested. Please please PLEASE use with extreme caution, this stuff can be very unpleasant in large amounts.
Thursday, 14. January 2010
My bottom line advice to JWH-018 newbies is to keep two basic concepts in mind:
1. You almost cannot use TOO LITTLE to get SOME effect — so use in teensy tiny amounts to start with… and even after you’ve got a feel for how much does how much — increase dosage by likewise teeny tiny amounts.
2. You almost cannot wait TOO LONG to let it do what it’s gonna do — so be very very patient and just let it ride. Piling more on while the first hit or two are still up and coming is a sure way to have a very unpleasant experience.
Friday, 29. January 2010
WARNING, PLEASE READ!!!!!!!!!!!!!!!!!!!!!!!!!!!. I have used JWH-018 because i am on probation and can not smoke weed. I have developed a severe addiction to the substance and it has really messed me up. I stoped smoking it and starting from day 1, i could not sleep. I got an average of 3 hours of sleep at night, i lost about 5 lb’s from loss of appatite, and i have been having fits of rage (ither from loss of sleep, or withdrawl). I would sudjest that you do not mess with this drug. As many of my friends are also addicted and are having the same problems as me. After about 1 full week of not being in contact with this drug my body is still having withdrawls and i am going to a doctor to help me. I would avoid this drug if you don’t want this to happen to you
Friday, 29. January 2010
Could you not try and taper off? If sleeping and eating are your main issues, why not try taking a lower than usual dose before your meal in the evening and before bed? Then, you wouldn’t be smoking it continuously to get high, only to treat those withdrawals. Gradually, you can reduce the amounts and stop taking before either the meal or bed and eventually stop all together.
Friday, 29. January 2010
For everyone saying you can go crazy, end up hospitalized, and all that..i have to tell you this.. i was on my way to a hookah lounge this past tuesday and one of my close friends who is on probation smoked an entire blunt of serinty. 1 whole gram. he DID NOT go to the hospital, he DID NOT go insane.. oh and also, in the town in which i live, i can go to gas stations and buy serenity.. im not sure of the amounts in the bags but the prices are.. $20, $45 and $70 this of things this way.. if marijuana wasnt discovered until now, there would be forums and rumors on the internet about it too.. tobacco is terrible for someone to smoke, but its legal and people are ok with it.. nicotine is a drug and if enough is smoked, you get a buzz. same with caffeine. why are these things ok and marijuana isnt? serenity now is not a bad thing.. but that doesnt mean its a good thing.. but i think ill just stick to the herb
Sunday, 31. January 2010
It’s easier for people to blame a drug than challenge why they may be having severe reactions.
Drugs are always taking the wrap for peoples psychological issues and stupidity.
Tuesday, 2. February 2010
i have been putting jwh 018 on my own herd and it work great i was wondering if it would be any better on weed
Wednesday, 3. February 2010
The most reasonable and safe method of consumption I have found is from a post on Drugs-Forum, which I will now paraphrase and expand upon.
Note, I have tried this, it works, it is the bee’s knees. I do not know why anyone would bother eyeballing and smoking this extremely powerful concentrated agent, when it can so effectively be regulated through the following solvent method.
Truthfully, I cannot even see the reason in dissolving the solvent onto a smokeable substrate, except for continuance of the social ritual of “smoking the bud”. But that is a great deal of work and still not very exact for the kind of potency and sensitivity we are talking about with professional lab-grade chemical. There is simply no need to smoke or vape, or risk any possibility of OD or The Fear, with the ease of this method and the long-term storage advantages inherent in the method.
Dissolve 250mg of JWH into 100mL of 190-proof Everclear. You must use 190 proof Everclear, which is available in my local liquor store down the street but may also be ordered online.
The math holds, so if you have 1000mg (1 gram) of JWH, dissolve into 400mL of 190-proof Everclear. I have personally done this with half-and-half of JWH-018 and JWH-073, 500mg a piece into 400mL Everclear. I’d recommend pouring the Everclear into a clear wide-mouthed receptacle with a “mL” scale on the side, like one of those large Pyrex measuring cups or beakers.
Most of the JWH will dissolve in the Everclear, except for a very small pile which will settle at the bottom. You will want to crush this up by using something like a wooden spoon or potato masher thrust down into the liquid and gently poking and scraping at the remnants of powder. Let the liquid resettle until you see more flakes at the bottom, and repeat poking and grinding. Let settle and repeat again and again, be patient, takes a bit of time but not too long and soooo worth it. Note that there is absolutely NO heating necessary, and it is quite stupid to be heating grain alcohol in your kitchen anyway. You do not need to heat anything, just use a little elbow grease to get your solution clear of any remaining flakes and granules.
Eventually you have a perfectly dissolved JWH solution which can be stored in the freezer or fridge, in a liquor bottle or, even better, a white wine bottle with a screwcap (no cork!) works great. It will store indefinitely.
With this solution, you are getting 2.5 milligrams of JWH per single milliliter of fluid.
You need a way to measure and dose by the milliliter.
Get a 3mL 22g syringe, I prefer with needle for precision but be careful with that needle waving around. You can buy these syringes in singles, ten packs, hundred packs online for cheap. I recommend a ten pack, costs about ten bucks.
Now, when ready, pour just a tiny tiny bit of your JWH juice into a shallow wide glass or small bowl. Slurp up 2 milliters of the stuff into your syringe for a 5 milligram dose (good starting reference point, very average dose). Pour whatever is left in your staging glass back into your storage bottle with aid of a small funnel. Remember to wash that staging glass very very well with dish detergent later.
Now you can inject the 2 milliliters in your syringe into your drinking vessel of choice, top with a small shot of pomegranate juice or other preferred cool beverage, knock it back….off you go.
One could conceivably procure a fair amount of JWH now, make several batches of the solution described above, and store away in the freezer or other cool dark place for years, perhaps decades, deftly weathering inevitable prohibition by various and sundry rampaging government agencies. Cheers!
Friday, 5. February 2010
Now that JWH-018 and 073 have been made illegal in Kansas and Ohio, how many other States are going to follow suit?
How are these “forensic experts” in Kansas testing the blend labeled K2??(that blend was specifically named in the hearings), what “scientific test” were run to make them announce they discovered it to be MUCH stronger than THC?? Did the partake in the “study” themselves??
The general statements made by these so called experts in the case is enough to make you sick, clueless legislators to be sure,
from my reading it was a very small lab in Germany that finally broke through the decoding and “discovered” the JWH chemicals in Spice, it seems no other “Big” Labs were able to detect it through many trials/tests.
The Legislature passed the ban in Kansas 36-1, the One that voted nay replied he thought it was extreme and unnecessary moves to ban it, and the passing was a result of reacting to hysteria and now NO RESEARCH will be able to be done on it in Kansas or Ohio.
The only good thing I can hope for is that looking at Salvia as an example, some states have banned it or made it illegal while others have decided there are BETTER things that need worrying about besides what legal alternatives adults chose to partake of, and try to make it illegal.
Friday, 5. February 2010
Where do you have proof or a fact that those states were banned for jwh-018 .. you state ohio and kansas are banned can you proof this to us!